Arm Yourselves for the Upcoming (Genetics) Revolution
Osama’s Sister’s Brother
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Barry Starr","firstName":"Dr. Barry","lastName":"Starr","slug":"dr-barry-starr","email":"bstarr@thetech.org","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Dr. Barry Starr (\u003ca href=\"https://twitter.com/geneticsboy\">@geneticsboy\u003c/a>) is a Geneticist-in-Residence at The Tech Museum of Innovation in San Jose, CA and runs their Stanford at The Tech program. The program is part of an ongoing collaboration between the \u003ca href=\"http://genetics.stanford.edu/\">Stanford Department of Genetics\u003c/a> and \u003ca href=\"http://www.thetech.org/\">The Tech Museum of Innovation\u003c/a>. Together these two partners created the \u003ca href=\"http://www.thetech.org/exhibits/permanent/index.php?sGalKey=gtwt&galKey=lt\">Genetics: Technology with a Twist\u003c/a> exhibition.\r\n\r\nYou can also see \u003ca href=\"https://ww2.kqed.org/science/author/dr-barry-starr/\">additional posts by Barry at KQED Science\u003c/a>, and read his \u003ca href=\"http://science.kqed.org/quest/author/dr-barry-starr/\">previous contributions\u003c/a> to \u003ca href=\"http://science.kqed.org/quest/\">QUEST\u003c/a>, a project dedicated to exploring the Science of Sustainability.","avatar":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g","twitter":"geneticsboy","facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"science","roles":["author"]},{"site":"quest","roles":["subscriber"]}],"headData":{"title":"Dr. Barry Starr | 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FM","link":"/"}},"quest_42743":{"type":"posts","id":"quest_42743","meta":{"index":"posts_1591205157","site":"quest","id":"42743","score":null,"sort":[1345475213000]},"guestAuthors":[],"slug":"arm-yourselves-for-the-upcoming-genetics-revolution","title":"Arm Yourselves for the Upcoming (Genetics) Revolution","publishDate":1345475213,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cfigure id=\"attachment_42745\" class=\"wp-caption alignnone\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/stanfordatthetech/\" rel=\"attachment wp-att-42745\">\u003cimg class=\"size-full wp-image-42745\" title=\"StanfordAtTheTech\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/StanfordAtTheTech.jpg\" alt=\"\" width=\"640\" height=\"367\" srcset=\"https://ww2.kqed.org/app/uploads/sites/39/2012/08/StanfordAtTheTech.jpg 640w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/StanfordAtTheTech-400x229.jpg 400w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">A multipronged approach to increasing genetics understanding.\u003c/figcaption>\u003c/figure>\n\u003cp>In the not too distant future, we’ll all have a map of our DNA in our hands. And lots of studies show that most of us are woefully unprepared for this latest genetic revolution. (See the links at the end for a selection of these studies.)\u003c/p>\n\u003cp>As a nation, we aren’t teaching the right genetics in our schools. And for those of us out of school, the situation is, if anything, even worse. By and large we lack the fundamental knowledge needed to properly interpret the avalanche of data headed our way.\u003c/p>\n\u003cp>Without this kind of knowledge, we are sure to get bamboozled by hucksters out there willing to sell us the “right” snake oil based on our DNA data. Even scarier, we may not make the right health decisions based on our DNA. And don’t necessarily count on your doctor for help navigating your way through these data. They are often as unprepared as the rest of us.\u003c/p>\n\u003cfigure id=\"attachment_42768\" class=\"wp-caption alignright\" style=\"max-width: 150px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/blaschkos_lines.jpg\">\u003cimg class=\"size-full wp-image-42768\" title=\"blaschkos_lines\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/blaschkos_lines.jpg\" alt=\"\" width=\"150\" height=\"200\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Chimeras are so cool! Sometimes these lines become apparent in chimeras under UV light.\u003c/figcaption>\u003c/figure>\n\u003cp>This is a big reason that the \u003ca href=\"http://genetics.stanford.edu/outreach/tech.html\">Stanford at The Tech program\u003c/a> has decided to publish the book, \u003cem>\u003ca href=\"http://genetics.thetech.org/book-titles\">When Will Broccoli Taste like Chocolate?\u003c/a>\u003c/em> (you can buy it from Amazon \u003ca href=\"http://www.amazon.com/gp/product/1477578714/ref=as_li_qf_sp_asin_il_tl?ie=UTF8&camp=1789&creative=9325&creativeASIN=1477578714&linkCode=as2&tag=staatthetec-20\">here\u003c/a>). It is a book that teaches genetics in a fun way by focusing on interesting cases and explaining the genetics behind them. Without even trying, you’ll get the solid footing you need to interpret your DNA. Or at the very least understand other people’s interpretations!\u003c/p>\n\u003cp>One of my favorite parts is the section on chimeras. Chimeras are fraternal twins who fused together at a very early stage of development. They are a single person who has one set of cells (and so one set of DNA) from one twin and another set of cells (and DNA) from the other twin.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>These chimeras don’t have two heads and four arms or anything like that. In fact, their differences are usually so subtle that they are invisible to the naked eye. They are often revealed only after they take some sort of genetic test (like a \u003ca href=\"http://www.mymultiplesclerosis.co.uk/misc/chimera.html\">paternity test\u003c/a> or a \u003ca href=\"http://www.katewerk.com/chimera.html\">tissue typing test\u003c/a> to find a new organ). And then what a revelation! Often the tests come back saying the chimera is not the parent of his or her children.\u003c/p>\n\u003cp>Chimeras are a great way to learn about DNA, genes, genetic tests and so on. And as you’ll see in the excerpt below, once you add in a link to a \u003ca href=\"http://www.csiguide.com/episodedetail.aspx?csi=157\">CSI episode\u003c/a> where a rapist almost gets away because he is a chimera, you end up with a fascinating read.\u003c/p>\n\u003cp>\u003ca href=\"http://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/excerpt500wwbtlc/\" rel=\"attachment wp-att-42744\">\u003cimg class=\"aligncenter size-full wp-image-42744\" title=\"Excerpt500WWBTLC\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/Excerpt500WWBTLC.gif\" alt=\"\" width=\"500\" height=\"755\">\u003c/a>\u003c/p>\n\u003cp>The story goes on to explain why a chimera isn't torn apart by its immune system, other ways besides chimeras to have multiple DNAs and lots more.\u003c/p>\n\u003cp>For parents and parents-to-be, there is a section on eye and hair color so they can understand how their children ended up with the coloring they got. For example, blue-eyed parents can breathe a sigh of relief if they have a green or brown eyed child because we show that despite what your high school biology teacher told you, this can and does happen. Parents-to-be can even use this information to predict what hair and eye color their children are most likely to have!\u003c/p>\n\u003cfigure id=\"attachment_42769\" class=\"wp-caption alignright\" style=\"max-width: 150px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/browneye/\" rel=\"attachment wp-att-42769\">\u003cimg class=\"size-full wp-image-42769\" title=\"BrownEye\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/BrownEye.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye.jpg 150w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-32x32.jpg 32w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-64x64.jpg 64w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-96x96.jpg 96w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-128x128.jpg 128w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-75x75.jpg 75w\" sizes=\"(max-width: 150px) 100vw, 150px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">This person could have had blue eyed parents.\u003c/figcaption>\u003c/figure>\n\u003cp>For people who want to know how embryos from different species decide whether to be a boy or a girl, there is a great section on Nemo the clownfish. And there is a cool section on all the genetic information we can get from poop. And...\u003c/p>\n\u003cp>Add to this book our \u003ca href=\"http://genetics.stanford.edu/outreach/tech.html\">Stanford at The Tech\u003c/a> program that provides hands-on activities at \u003ca href=\"http://www.thetech.org/\">The Tech Museum\u003c/a> in San Jose (as well as at other venues) and our \u003ca href=\"http://genetics.thetech.org/\">Understanding Genetics\u003c/a> website, and you get a full frontal assault on the lack of genetics knowledge out there. We aim to demystify genetics and show how entertaining and interesting it really is. Perhaps a better title for the book might have been, \u003cem>When Will Genetics be like a Day at Disneyland?\u003c/em>. That day may be here sooner than you think.\u003c/p>\n\u003cp>For fun, here is a quick quiz I whipped up to test your genetics IQ. To make things interesting, the first person to get them all right gets a free copy of \u003cem>\u003ca href=\"http://genetics.thetech.org/book-titles\">When Will Broccoli Taste like Chocolate?\u003c/a>\u003c/em>. You can answer here, on \u003ca href=\"http://www.facebook.com/UnderstandGenetics\">Facebook\u003c/a> or, if you’re like me and you’d rather use email, send your answers to askageneticist@thetech.org. Good luck and enjoy!\u003c/p>\n\u003cp>1) Should you necessarily be scared if you find out you are 10 times more likely to get a rare cancer?\u003c/p>\n\u003cp>2) If you look like your mom, are you more likely to get the diseases that run in her family or your dad’s family?\u003c/p>\n\u003cp>3) If you have the recessive disease sickle cell anemia, should your kids be tested to see if they are carriers?\u003c/p>\n\u003cp>4) If you look like your dad, did you get more of his DNA?\u003c/p>\n\u003cp>5) If you flip a coin and get heads ten times in a row, what are the chances that the next flip will be a head?\u003c/p>\n\u003cp>6) True or false: Each cell in your body has the same DNA.\u003c/p>\n\u003cp>\u003cstrong>Studies cataloging the public’s lack of genetics knowledge:\u003c/strong>\u003cem>\u003cbr>\n\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/19039252\">\u003cbr>\nAustralian study on public knowledge of human genetics and health\u003c/a>.\u003cbr>\n\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/20512408\">\u003cbr>\nMisunderstandings concerning genetics among patients confronting genetic disease.\u003c/a>\u003c/em>\u003c/p>\n\u003cp>\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/18245328\">Essay contest reveals misconceptions of high school students in genetics content\u003c/a>.\u003c/p>\n\u003cp>\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/21885828\">A comprehensive analysis of high school genetics standards: are states keeping pace with modern genetics?\u003c/a>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>You can buy the book from Amazon \u003ca href=\"http://www.amazon.com/gp/product/1477578714/ref=as_li_qf_sp_asin_il_tl?ie=UTF8&camp=1789&creative=9325&creativeASIN=1477578714&linkCode=as2&tag=staatthetec-20\">here\u003c/a>.\u003c/p>\n\n","blocks":[],"excerpt":"As a nation, we aren’t teaching the right genetics in our schools. And for those of us out of school, the situation is, if anything, even worse. By and large we lack the fundamental knowledge needed to properly interpret the avalanche of data headed our way. ","status":"publish","parent":0,"modified":1346782049,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":25,"wordCount":971},"headData":{"title":"Arm Yourselves for the Upcoming (Genetics) Revolution | KQED","description":"As a nation, we aren’t teaching the right genetics in our schools. And for those of us out of school, the situation is, if anything, even worse. By and large we lack the fundamental knowledge needed to properly interpret the avalanche of data headed our way. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Arm Yourselves for the Upcoming (Genetics) Revolution","datePublished":"2012-08-20T15:06:53.000Z","dateModified":"2012-09-04T18:07:29.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"42743 http://science.kqed.org/quest/?p=42743","disqusUrl":"https://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/","disqusTitle":"Arm Yourselves for the Upcoming (Genetics) Revolution","path":"/quest/42743/arm-yourselves-for-the-upcoming-genetics-revolution","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cfigure id=\"attachment_42745\" class=\"wp-caption alignnone\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/stanfordatthetech/\" rel=\"attachment wp-att-42745\">\u003cimg class=\"size-full wp-image-42745\" title=\"StanfordAtTheTech\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/StanfordAtTheTech.jpg\" alt=\"\" width=\"640\" height=\"367\" srcset=\"https://ww2.kqed.org/app/uploads/sites/39/2012/08/StanfordAtTheTech.jpg 640w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/StanfordAtTheTech-400x229.jpg 400w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">A multipronged approach to increasing genetics understanding.\u003c/figcaption>\u003c/figure>\n\u003cp>In the not too distant future, we’ll all have a map of our DNA in our hands. And lots of studies show that most of us are woefully unprepared for this latest genetic revolution. (See the links at the end for a selection of these studies.)\u003c/p>\n\u003cp>As a nation, we aren’t teaching the right genetics in our schools. And for those of us out of school, the situation is, if anything, even worse. By and large we lack the fundamental knowledge needed to properly interpret the avalanche of data headed our way.\u003c/p>\n\u003cp>Without this kind of knowledge, we are sure to get bamboozled by hucksters out there willing to sell us the “right” snake oil based on our DNA data. Even scarier, we may not make the right health decisions based on our DNA. And don’t necessarily count on your doctor for help navigating your way through these data. They are often as unprepared as the rest of us.\u003c/p>\n\u003cfigure id=\"attachment_42768\" class=\"wp-caption alignright\" style=\"max-width: 150px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/blaschkos_lines.jpg\">\u003cimg class=\"size-full wp-image-42768\" title=\"blaschkos_lines\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/blaschkos_lines.jpg\" alt=\"\" width=\"150\" height=\"200\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Chimeras are so cool! Sometimes these lines become apparent in chimeras under UV light.\u003c/figcaption>\u003c/figure>\n\u003cp>This is a big reason that the \u003ca href=\"http://genetics.stanford.edu/outreach/tech.html\">Stanford at The Tech program\u003c/a> has decided to publish the book, \u003cem>\u003ca href=\"http://genetics.thetech.org/book-titles\">When Will Broccoli Taste like Chocolate?\u003c/a>\u003c/em> (you can buy it from Amazon \u003ca href=\"http://www.amazon.com/gp/product/1477578714/ref=as_li_qf_sp_asin_il_tl?ie=UTF8&camp=1789&creative=9325&creativeASIN=1477578714&linkCode=as2&tag=staatthetec-20\">here\u003c/a>). It is a book that teaches genetics in a fun way by focusing on interesting cases and explaining the genetics behind them. Without even trying, you’ll get the solid footing you need to interpret your DNA. Or at the very least understand other people’s interpretations!\u003c/p>\n\u003cp>One of my favorite parts is the section on chimeras. Chimeras are fraternal twins who fused together at a very early stage of development. They are a single person who has one set of cells (and so one set of DNA) from one twin and another set of cells (and DNA) from the other twin.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>These chimeras don’t have two heads and four arms or anything like that. In fact, their differences are usually so subtle that they are invisible to the naked eye. They are often revealed only after they take some sort of genetic test (like a \u003ca href=\"http://www.mymultiplesclerosis.co.uk/misc/chimera.html\">paternity test\u003c/a> or a \u003ca href=\"http://www.katewerk.com/chimera.html\">tissue typing test\u003c/a> to find a new organ). And then what a revelation! Often the tests come back saying the chimera is not the parent of his or her children.\u003c/p>\n\u003cp>Chimeras are a great way to learn about DNA, genes, genetic tests and so on. And as you’ll see in the excerpt below, once you add in a link to a \u003ca href=\"http://www.csiguide.com/episodedetail.aspx?csi=157\">CSI episode\u003c/a> where a rapist almost gets away because he is a chimera, you end up with a fascinating read.\u003c/p>\n\u003cp>\u003ca href=\"http://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/excerpt500wwbtlc/\" rel=\"attachment wp-att-42744\">\u003cimg class=\"aligncenter size-full wp-image-42744\" title=\"Excerpt500WWBTLC\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/Excerpt500WWBTLC.gif\" alt=\"\" width=\"500\" height=\"755\">\u003c/a>\u003c/p>\n\u003cp>The story goes on to explain why a chimera isn't torn apart by its immune system, other ways besides chimeras to have multiple DNAs and lots more.\u003c/p>\n\u003cp>For parents and parents-to-be, there is a section on eye and hair color so they can understand how their children ended up with the coloring they got. For example, blue-eyed parents can breathe a sigh of relief if they have a green or brown eyed child because we show that despite what your high school biology teacher told you, this can and does happen. Parents-to-be can even use this information to predict what hair and eye color their children are most likely to have!\u003c/p>\n\u003cfigure id=\"attachment_42769\" class=\"wp-caption alignright\" style=\"max-width: 150px\">\u003ca href=\"http://ww2.kqed.org/quest/2012/08/20/arm-yourselves-for-the-upcoming-genetics-revolution/browneye/\" rel=\"attachment wp-att-42769\">\u003cimg class=\"size-full wp-image-42769\" title=\"BrownEye\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2012/08/BrownEye.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye.jpg 150w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-32x32.jpg 32w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-64x64.jpg 64w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-96x96.jpg 96w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-128x128.jpg 128w, https://ww2.kqed.org/app/uploads/sites/39/2012/08/BrownEye-75x75.jpg 75w\" sizes=\"(max-width: 150px) 100vw, 150px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">This person could have had blue eyed parents.\u003c/figcaption>\u003c/figure>\n\u003cp>For people who want to know how embryos from different species decide whether to be a boy or a girl, there is a great section on Nemo the clownfish. And there is a cool section on all the genetic information we can get from poop. And...\u003c/p>\n\u003cp>Add to this book our \u003ca href=\"http://genetics.stanford.edu/outreach/tech.html\">Stanford at The Tech\u003c/a> program that provides hands-on activities at \u003ca href=\"http://www.thetech.org/\">The Tech Museum\u003c/a> in San Jose (as well as at other venues) and our \u003ca href=\"http://genetics.thetech.org/\">Understanding Genetics\u003c/a> website, and you get a full frontal assault on the lack of genetics knowledge out there. We aim to demystify genetics and show how entertaining and interesting it really is. Perhaps a better title for the book might have been, \u003cem>When Will Genetics be like a Day at Disneyland?\u003c/em>. That day may be here sooner than you think.\u003c/p>\n\u003cp>For fun, here is a quick quiz I whipped up to test your genetics IQ. To make things interesting, the first person to get them all right gets a free copy of \u003cem>\u003ca href=\"http://genetics.thetech.org/book-titles\">When Will Broccoli Taste like Chocolate?\u003c/a>\u003c/em>. You can answer here, on \u003ca href=\"http://www.facebook.com/UnderstandGenetics\">Facebook\u003c/a> or, if you’re like me and you’d rather use email, send your answers to askageneticist@thetech.org. Good luck and enjoy!\u003c/p>\n\u003cp>1) Should you necessarily be scared if you find out you are 10 times more likely to get a rare cancer?\u003c/p>\n\u003cp>2) If you look like your mom, are you more likely to get the diseases that run in her family or your dad’s family?\u003c/p>\n\u003cp>3) If you have the recessive disease sickle cell anemia, should your kids be tested to see if they are carriers?\u003c/p>\n\u003cp>4) If you look like your dad, did you get more of his DNA?\u003c/p>\n\u003cp>5) If you flip a coin and get heads ten times in a row, what are the chances that the next flip will be a head?\u003c/p>\n\u003cp>6) True or false: Each cell in your body has the same DNA.\u003c/p>\n\u003cp>\u003cstrong>Studies cataloging the public’s lack of genetics knowledge:\u003c/strong>\u003cem>\u003cbr>\n\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/19039252\">\u003cbr>\nAustralian study on public knowledge of human genetics and health\u003c/a>.\u003cbr>\n\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/20512408\">\u003cbr>\nMisunderstandings concerning genetics among patients confronting genetic disease.\u003c/a>\u003c/em>\u003c/p>\n\u003cp>\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/18245328\">Essay contest reveals misconceptions of high school students in genetics content\u003c/a>.\u003c/p>\n\u003cp>\u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/21885828\">A comprehensive analysis of high school genetics standards: are states keeping pace with modern genetics?\u003c/a>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>You can buy the book from Amazon \u003ca href=\"http://www.amazon.com/gp/product/1477578714/ref=as_li_qf_sp_asin_il_tl?ie=UTF8&camp=1789&creative=9325&creativeASIN=1477578714&linkCode=as2&tag=staatthetec-20\">here\u003c/a>.\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/42743/arm-yourselves-for-the-upcoming-genetics-revolution","authors":["6177"],"categories":["quest_4","quest_12"],"tags":["quest_3590","quest_1197","quest_11373","quest_3974","quest_13202","quest_2532","quest_3319"],"featImg":"quest_42745","label":"quest"},"quest_19224":{"type":"posts","id":"quest_19224","meta":{"index":"posts_1591205157","site":"quest","id":"19224","score":null,"sort":[1304959203000]},"guestAuthors":[],"slug":"osama%e2%80%99s-sister%e2%80%99s-brother","title":"Osama’s Sister’s Brother","publishDate":1304959203,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/05/Osama1.jpg\" alt=\"\">\u003c/a>\u003cem>DNA tests were able to confirm with a 99.9% certainty that\u003cbr>Osama bin Laden has been killed.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>One of the key ways the U.S. government confirmed that they had killed Osama bin Laden was using genetic tests. What they did was take DNA from the corpse and compare it to known relatives of Osama bin Laden (or at the very least to his sister). From this they concluded that there was a 99.9% chance that the dead man was Osama bin Laden.\u003c/p>\n\u003cp>Unless they had a sample of Osama’s DNA, these kinds of tests can’t necessarily prove beyond a shadow of a doubt that the man killed was Osama. What it can do, for example, is say that the man killed was Osama’s sister’s brother. If all the other brothers are accounted for and there aren’t any unknown brothers out there, then this is him.\u003cbr>\n\u003c!--more-->\u003cbr>\nThis shows why it is so important to have lots of relatives to test. For example, if they also tested one or more of his children, then they could conclude that the man killed was the father of Osama’s children and the brother of Osama’s sister. Unless Osama had an unknown brother who fathered his children, then the dead man in Pakistan would certainly be Osama bin Laden. \u003c/p>\n\u003cp>Of course they didn’t rely just on the DNA (although these results are very strong). They also used fancy biometric recognition software and eyewitness testimony to confirm that the dead man is Osama bin Laden.\u003c/p>\n\u003cp>\u003cstrong>Testing DNA\u003c/strong>\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>So how’d they do the actual DNA testing? They wouldn’t have had time to sequence all of his DNA but that’s not a big deal. No one would do that to identify a suspect anyway.\u003c/p>\n\u003cp>Most likely, they did a more extensive version of a run-of-the-mill paternity test. When given a high priority, these tests can easily be done in less than 24 hours.\u003c/p>\n\u003cp>In paternity-like tests, scientists compare the DNA of the related people at multiple spots in the genome. They look at parts of our DNA that tend to be different between unrelated people. If people share a lot of them in common in the right ways, then they are related.\u003c/p>\n\u003cp>These spots go by lots of different names--microsatellites, simple sequence repeats (SSRs), short tandem repeats (STRs), variable number tandem repeats (VNTRs)--but we’ll call them STRs here. STRs are bits of DNA where the sequence is repeated over and over, back to back. \u003c/p>\n\u003cp>Remember, DNA is made up of four chemical \"letters\" (or nucleotides) that are usually abbreviated as A, G, T, and C. So an STR is a string of letters that is repeated. What makes them useful here is that different people can have different numbers of these repeats.\u003c/p>\n\u003cp>Imagine the set of DNA letters AGTC. One person might have 10 of these in a row. And another might have 11 or 9.\u003c/p>\n\u003cp>Of course, lots of people will have 10 of these repeats. That is why scientists can't look at just one STR. Here in the U.S., forensic scientists have chosen 13 of them to tell people apart. Since the government only had a few relatives to compare Osama’s DNA to, they almost certainly looked at many more spots. The more spots you look at, the more solid is the evidence that two people are related.\u003c/p>\n\u003cp>To get enough DNA to see, scientists need to use something called the polymerase chain reaction or PCR. This technique is a really fast way to make lots of copies of a bit of someone’s DNA. \u003c/p>\n\u003cp>In PCR, scientists use a special protein called a \"polymerase.\" Its job is to copy DNA. Scientists tell the protein what DNA to copy by giving it starting and ending points, called \"primers.\" \u003c/p>\n\u003cp>Primers are small segments of DNA that match the part of the DNA a scientist is interested in. The protein then copies everything between the two primers. \u003c/p>\n\u003cp>Here the government would have premade all of the primers on each side of the STRs they wanted to test. They would have also worked out all of the reaction conditions so they could get the results in just a few hours. A single PCR reaction would look something like this:\u003c/p>\n\u003cp>\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/05/PCR11.gif\" align=\"center\">\u003c/p>\n\u003cp>If someone has a different number of repeats, then they'll have a different size of copied DNA. Imagine our example above. If I have 10 copies of AGTC and you have 11, then my copied piece of DNA will be 4 letters shorter. \u003c/p>\n\u003cp>Osama’s sister’s DNA and the DNA from the man who died in the Pakistani compound must have shared lots of these STRs. So many in fact, that there was a 99.9% chance that they were brother and sister.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7749295 -122.4194155\u003c/p>\n\n","blocks":[],"excerpt":"Scientists could definitely get DNA results from Osama bin Laden in less than 24 hours. And they could conclude with high certainty that the man killed was Osama bin Laden.","status":"publish","parent":0,"modified":1309991431,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":22,"wordCount":829},"headData":{"title":"Osama’s Sister’s Brother | KQED","description":"Scientists could definitely get DNA results from Osama bin Laden in less than 24 hours. And they could conclude with high certainty that the man killed was Osama bin Laden.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Osama’s Sister’s Brother","datePublished":"2011-05-09T16:40:03.000Z","dateModified":"2011-07-06T22:30:31.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"19224 http://www.kqed.org/quest/blog/2011/05/09/osama%e2%80%99s-sister%e2%80%99s-brother/","disqusUrl":"https://ww2.kqed.org/quest/2011/05/09/osama%e2%80%99s-sister%e2%80%99s-brother/","disqusTitle":"Osama’s Sister’s Brother","path":"/quest/19224/osama%e2%80%99s-sister%e2%80%99s-brother","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/05/Osama1.jpg\" alt=\"\">\u003c/a>\u003cem>DNA tests were able to confirm with a 99.9% certainty that\u003cbr>Osama bin Laden has been killed.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>One of the key ways the U.S. government confirmed that they had killed Osama bin Laden was using genetic tests. What they did was take DNA from the corpse and compare it to known relatives of Osama bin Laden (or at the very least to his sister). From this they concluded that there was a 99.9% chance that the dead man was Osama bin Laden.\u003c/p>\n\u003cp>Unless they had a sample of Osama’s DNA, these kinds of tests can’t necessarily prove beyond a shadow of a doubt that the man killed was Osama. What it can do, for example, is say that the man killed was Osama’s sister’s brother. If all the other brothers are accounted for and there aren’t any unknown brothers out there, then this is him.\u003cbr>\n\u003c!--more-->\u003cbr>\nThis shows why it is so important to have lots of relatives to test. For example, if they also tested one or more of his children, then they could conclude that the man killed was the father of Osama’s children and the brother of Osama’s sister. Unless Osama had an unknown brother who fathered his children, then the dead man in Pakistan would certainly be Osama bin Laden. \u003c/p>\n\u003cp>Of course they didn’t rely just on the DNA (although these results are very strong). They also used fancy biometric recognition software and eyewitness testimony to confirm that the dead man is Osama bin Laden.\u003c/p>\n\u003cp>\u003cstrong>Testing DNA\u003c/strong>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>So how’d they do the actual DNA testing? They wouldn’t have had time to sequence all of his DNA but that’s not a big deal. No one would do that to identify a suspect anyway.\u003c/p>\n\u003cp>Most likely, they did a more extensive version of a run-of-the-mill paternity test. When given a high priority, these tests can easily be done in less than 24 hours.\u003c/p>\n\u003cp>In paternity-like tests, scientists compare the DNA of the related people at multiple spots in the genome. They look at parts of our DNA that tend to be different between unrelated people. If people share a lot of them in common in the right ways, then they are related.\u003c/p>\n\u003cp>These spots go by lots of different names--microsatellites, simple sequence repeats (SSRs), short tandem repeats (STRs), variable number tandem repeats (VNTRs)--but we’ll call them STRs here. STRs are bits of DNA where the sequence is repeated over and over, back to back. \u003c/p>\n\u003cp>Remember, DNA is made up of four chemical \"letters\" (or nucleotides) that are usually abbreviated as A, G, T, and C. So an STR is a string of letters that is repeated. What makes them useful here is that different people can have different numbers of these repeats.\u003c/p>\n\u003cp>Imagine the set of DNA letters AGTC. One person might have 10 of these in a row. And another might have 11 or 9.\u003c/p>\n\u003cp>Of course, lots of people will have 10 of these repeats. That is why scientists can't look at just one STR. Here in the U.S., forensic scientists have chosen 13 of them to tell people apart. Since the government only had a few relatives to compare Osama’s DNA to, they almost certainly looked at many more spots. The more spots you look at, the more solid is the evidence that two people are related.\u003c/p>\n\u003cp>To get enough DNA to see, scientists need to use something called the polymerase chain reaction or PCR. This technique is a really fast way to make lots of copies of a bit of someone’s DNA. \u003c/p>\n\u003cp>In PCR, scientists use a special protein called a \"polymerase.\" Its job is to copy DNA. Scientists tell the protein what DNA to copy by giving it starting and ending points, called \"primers.\" \u003c/p>\n\u003cp>Primers are small segments of DNA that match the part of the DNA a scientist is interested in. The protein then copies everything between the two primers. \u003c/p>\n\u003cp>Here the government would have premade all of the primers on each side of the STRs they wanted to test. They would have also worked out all of the reaction conditions so they could get the results in just a few hours. A single PCR reaction would look something like this:\u003c/p>\n\u003cp>\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/05/PCR11.gif\" align=\"center\">\u003c/p>\n\u003cp>If someone has a different number of repeats, then they'll have a different size of copied DNA. Imagine our example above. If I have 10 copies of AGTC and you have 11, then my copied piece of DNA will be 4 letters shorter. \u003c/p>\n\u003cp>Osama’s sister’s DNA and the DNA from the man who died in the Pakistani compound must have shared lots of these STRs. So many in fact, that there was a 99.9% chance that they were brother and sister.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7749295 -122.4194155\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/19224/osama%e2%80%99s-sister%e2%80%99s-brother","authors":["6177"],"categories":["quest_4"],"tags":["quest_3523","quest_3590","quest_1197","quest_3616","quest_3658","quest_3690","quest_3695","quest_3696","quest_3709","quest_3784"],"featImg":"quest_19250","label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. 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You ask the questions. You decide what Bay Curious investigates. 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Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. 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No other part of the globe has experienced such dynamic political and social change in recent years.","airtime":"SAT 3am-4am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Inside-Europe-Podcast-Tile-300x300-1.jpg","meta":{"site":"news","source":"Deutsche Welle"},"link":"/radio/program/inside-europe","subscribe":{"apple":"https://itunes.apple.com/us/podcast/inside-europe/id80106806?mt=2","tuneIn":"https://tunein.com/radio/Inside-Europe-p731/","rss":"https://partner.dw.com/xml/podcast_inside-europe"}},"latino-usa":{"id":"latino-usa","title":"Latino USA","airtime":"MON 1am-2am, SUN 6pm-7pm","info":"Latino USA, the radio journal of news and culture, is the only national, English-language radio program produced from a Latino perspective.","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/latinoUsa.jpg","officialWebsiteLink":"http://latinousa.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/latino-usa","subscribe":{"npr":"https://rpb3r.app.goo.gl/xtTd","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=79681317&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Latino-USA-p621/","rss":"https://feeds.npr.org/510016/podcast.xml"}},"live-from-here-highlights":{"id":"live-from-here-highlights","title":"Live from Here Highlights","info":"Chris Thile steps to the mic as the host of Live from Here (formerly A Prairie Home Companion), a live public radio variety show. 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Updated Monday through Friday at about 3:30 p.m. PT.","airtime":"MON-FRI 4pm-4:30pm, MON-WED 6:30pm-7pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Marketplace-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.marketplace.org/","meta":{"site":"news","source":"American Public Media"},"link":"/radio/program/marketplace","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=201853034&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/APM-Marketplace-p88/","rss":"https://feeds.publicradio.org/public_feeds/marketplace-pm/rss/rss"}},"mindshift":{"id":"mindshift","title":"MindShift","tagline":"A podcast about the future of learning and how we raise our kids","info":"The MindShift podcast explores the innovations in education that are shaping how kids learn. Hosts Ki Sung and Katrina Schwartz introduce listeners to educators, researchers, parents and students who are developing effective ways to improve how kids learn. We cover topics like how fed-up administrators are developing surprising tactics to deal with classroom disruptions; how listening to podcasts are helping kids develop reading skills; the consequences of overparenting; and why interdisciplinary learning can engage students on all ends of the traditional achievement spectrum. This podcast is part of the MindShift education site, a division of KQED News. KQED is an NPR/PBS member station based in San Francisco. You can also visit the MindShift website for episodes and supplemental blog posts or tweet us \u003ca href=\"https://twitter.com/MindShiftKQED\">@MindShiftKQED\u003c/a> or visit us at \u003ca href=\"/mindshift\">MindShift.KQED.org\u003c/a>","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Mindshift-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED MindShift: How We Will Learn","officialWebsiteLink":"/mindshift/","meta":{"site":"news","source":"kqed","order":"2"},"link":"/podcasts/mindshift","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/mindshift-podcast/id1078765985","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM1NzY0NjAwNDI5","npr":"https://www.npr.org/podcasts/464615685/mind-shift-podcast","stitcher":"https://www.stitcher.com/podcast/kqed/stories-teachers-share","spotify":"https://open.spotify.com/show/0MxSpNYZKNprFLCl7eEtyx"}},"morning-edition":{"id":"morning-edition","title":"Morning Edition","info":"\u003cem>Morning Edition\u003c/em> takes listeners around the country and the world with multi-faceted stories and commentaries every weekday. Hosts Steve Inskeep, David Greene and Rachel Martin bring you the latest breaking news and features to prepare you for the day.","airtime":"MON-FRI 3am-9am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Morning-Edition-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/morning-edition/","meta":{"site":"news","source":"npr"},"link":"/radio/program/morning-edition"},"onourwatch":{"id":"onourwatch","title":"On Our Watch","tagline":"Police secrets, unsealed","info":"For decades, the process for how police police themselves has been inconsistent – if not opaque. In some states, like California, these proceedings were completely hidden. After a new police transparency law unsealed scores of internal affairs files, our reporters set out to examine these cases and the shadow world of police discipline. 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