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Standen","firstName":"Amy","lastName":"Standen","slug":"amystanden","email":"astanden@kqed.org","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Amy Standen (@amystanden) is co-host of #\u003ca href=\"https://ww2.kqed.org/news/programs/the-leap\">TheLeapPodcast\u003c/a> (subscribe on iTunes or Stitcher!) and host of KQED and PBSDigital Studios' science video series, \u003ca href=\"https://www.youtube.com/user/KQEDDeepLook\">Deep Look\u003c/a>. Her science radio stories appear on KQED and NPR.\r\n\r\nEmail her at astanden@kqed.org","avatar":"https://secure.gravatar.com/avatar/3d021b72de685a788b0487b059d0a6a1?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"news","roles":["subscriber"]},{"site":"futureofyou","roles":["subscriber"]},{"site":"stateofhealth","roles":["subscriber"]},{"site":"science","roles":["editor"]},{"site":"quest","roles":["subscriber"]}],"headData":{"title":"Amy Standen | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/3d021b72de685a788b0487b059d0a6a1?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/3d021b72de685a788b0487b059d0a6a1?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/amystanden"},"acurry":{"type":"authors","id":"6444","meta":{"index":"authors_1591205172","id":"6444","found":true},"name":"Arwen Curry","firstName":"Arwen","lastName":"Curry","slug":"acurry","email":"acurry@KQED.org","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Arwen Curry is Associate Producer of TV at KQED Science. She comes to KQED from documentary film, and is director of \u003cem>Worlds of Ursula K. Le Guin\u003c/em>, a feature documentary about the influential science fiction writer. She was Associate Producer of the films \u003cem>Regarding Susan Sontag\u003c/em>, \u003cem>American Jerusalem: Jews and the Making of San Francisco\u003c/em>, \u003cem>EAMES: The Architect & The Painter\u003c/em>, \u003cem>Utopia in Four Movements\u003c/em>, and co-produced and directed \u003cem>Stuffed\u003c/em>, a short film about compulsive hoarding. Arwen was editor of the punk magazine \u003cem>Maximum Rock 'n' Roll\u003c/em>, and has been a contributor to Radio Lab and McSweeney’s. She is a Bay Area native and a graduate of the UC Berkeley Graduate School of Journalism.","avatar":"https://secure.gravatar.com/avatar/59af0722ca76a9bcd9dd6da80e683e18?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"science","roles":["editor"]},{"site":"quest","roles":["leadcoordinator","subscriber"]}],"headData":{"title":"Arwen Curry | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/59af0722ca76a9bcd9dd6da80e683e18?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/59af0722ca76a9bcd9dd6da80e683e18?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/acurry"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"home","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"quest_17514":{"type":"posts","id":"quest_17514","meta":{"index":"posts_1591205157","site":"quest","id":"17514","score":null,"sort":[1415804432000]},"guestAuthors":[],"slug":"catching-up-on-sleep-science","title":"Catching Up on Sleep Science","publishDate":1415804432,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{},"content":"\u003cp>\u003cem>This video story was originally produced by \u003ca href=\"http://ww2.kqed.org/quest/author/sheraz-sadiq/\">Sheraz Sadiq\u003c/a> and was updated by\u003ca href=\"http://ww2.kqed.org/quest/author/lisalanders/\"> Lisa Landers\u003c/a> and \u003ca href=\"http://ww2.kqed.org/quest/author/acurry/\">Arwen Curry.\u003c/a>\u003c/em>\u003c/p>\n\u003cp>Be honest – do you ever brag about how little sleep you get? If so, you’re not alone. Humans are the only species that seems to deliberately deprive themselves of sleep. But if you’ve ever uttered a phrase like “I’ll sleep when I’m dead,” it’s time for a wake-up call, scientists say.\u003c/p>\n\u003cfigure id=\"attachment_72675\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear.jpg\">\u003cimg class=\"size-thumbnail wp-image-72675\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear-300x169.jpg\" alt=\"Sleep is common to all species that have been studied to date.\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Sleep is common to all species that have been studied to date.\u003c/figcaption>\u003c/figure>\n\u003cp>Researchers have long known that adequate sleep is critical for good health. Insufficient sleep \u003ca href=\"http://www.mayoclinic.org/diseases-conditions/insomnia/expert-answers/lack-of-sleep/faq-20057757\">impairs the immune system\u003c/a>, and is associated with everything from \u003ca href=\"http://www.hsph.harvard.edu/nutritionsource/sleep/\">obesity\u003c/a> to cardiovascular disease, stroke to cancer, depression to schizophrenia and \u003ca href=\"http://news.temple.edu/news/2014-03-18/chronic-sleep-disturbance-might-trigger-onset-alzheimer%E2%80%99s\">Alzheimer’s disease\u003c/a>. Now scientists are several steps closer to knowing how sleep keeps us healthy.\u003c/p>\n\u003cp>An important clue about sleep’s function surfaced in \u003ca href=\"http://www.nature.com/neuro/journal/v16/n2/full/nn.3303.html\">a 2013 study\u003c/a> published in the journal \u003cem>\u003ca href=\"http://www.nature.com/neuro/index.html\">Nature Neuroscience\u003c/a> \u003c/em>and conducted at the University of California-Berkeley. The study, by neuroscience professor Matthew Walker and his colleagues, showed that the structural changes the brain experiences as we age damage the quality of deep sleep. This hinders the brain’s ongoing ability to store memories.\u003c/p>\n\u003cfigure id=\"attachment_72671\" class=\"wp-caption alignleft\" style=\"max-width: 264px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800.jpg\">\u003cimg class=\"wp-image-72671 size-thumbnail\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800-264x169.jpg\" alt=\"Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley Photo by Arwen Curry.\" width=\"264\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley.\u003cbr> Photo by Arwen Curry.\u003c/figcaption>\u003c/figure>\n\u003cp>Scientists were already aware of a connection between sleep and memory – now they are developing a working hypothesis about how the mechanism actually works.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>“It’s almost as though your learning system is like a USB stick,” Walker said. “During the day you’re acquiring lots of information rapidly.” This information is lodged in an area of the brain called the hippocampus.\u003c/p>\n\u003cp>But when we sleep, this data is exported to “the hard drive of our brain,” a larger storage space called the cortex.\u003c/p>\n\u003cp>“When we wake up the next day, our USB stick has now been cleared out, so we can start to learn new information anew,” Walker said. “We’ve refreshed our learning capacity.”\u003c/p>\n\u003cp>The idea that we need less sleep as we age is a fallacy, he added. It now appears that the brain is physically unable to achieve the amount of slow-wave, non-rapid-eye-movement sleep needed to consolidate memories as we grow older. By the time we’re 50 years old, non-REM sleep has reduced by half compared to when we were 18 years old. By the time we’re 70, deep sleep is down to about 5 percent.\u003c/p>\n\u003cfigure id=\"attachment_72668\" class=\"wp-caption alignright\" style=\"max-width: 288px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\">\u003cimg class=\"wp-image-72668 size-full\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\" alt=\"Scientists use electric pulses to copy the rhythm of slow-wave sleep, which declines as we age.\" width=\"288\" height=\"162\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Scientists use electrical pulses to copy the rhythm of slow-wave sleep, which declines as we age.\u003c/figcaption>\u003c/figure>\n\u003cp>This research suggests that improving slow-wave sleep, which takes up about a quarter of the night, could slow the decline of memory as we age. Scientists are investigating \u003ca href=\"http://www.sciencedirect.com/science/article/pii/016643289390140L\">ways to use electrical stimulation to improve deep sleep in older people\u003c/a> by attaching electrodes to the scalp to create a mild current that mimics the pattern of slow-wave sleep.\u003c/p>\n\u003cp>The science of sleep has traditionally been abstract, but advances in imaging technology now allow scientists to peek inside the sleeping brain. In \u003ca href=\"http://www.urmc.rochester.edu/news/story/index.cfm?id=3956\">a groundbreaking 2013 study\u003c/a>, researchers at the University of Rochester Medical Center injected dyes into the brains of sleeping mice, and watched in real-time as the neurons in their brains shrank dramatically by about 60 percent. This increased the spaces between the brain cells, allowing cerebrospinal fluid to easily flow through and cleanse the brain of naturally occurring toxic waste.\u003c/p>\n\u003cfigure id=\"attachment_72672\" class=\"wp-caption alignleft\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800.jpg\">\u003cimg class=\"wp-image-72672 size-large\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800-640x360.jpg\" alt=\"This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse.\" width=\"640\" height=\"360\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse. Photo courtesy of the University of Rochester Medical Center.\u003c/figcaption>\u003c/figure>\n\u003cp>“It’s almost as though you’re sort of walking past one of those delightful posh hotels and during the day there’s lots of dirt that happens on the sidewalk,” said Walker. “And then at night, someone comes out with one of those pressure-jet washers and cleans it all out, so that it’s fresh and functional the next day. That’s exactly what we think is now happening during sleep at night.”\u003c/p>\n\u003cp>Of particular note is that chronic sleep deprivation contributes to \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/24887018\">the buildup of a toxic protein called beta-amyloid\u003c/a>, which is a predictor of Alzheimer’s disease.\u003c/p>\n\u003cp>Walker’s research also suggests strong connections between sleep and creativity and emotional regulation. But with all we’ve learned about sleep, there remains much more to be discovered.\u003c/p>\n\u003cp>“If you think about it,” said Walker, “we’ve understood the other three main biological drives – eating, drinking and reproducing – for many tens, if not hundreds, of years. But the fourth main biological drive, common across all species that we’ve studied, which is to sleep, remains that quintessential mystery.”\u003c/p>\n\u003cp>One thing is clear: \u003ca href=\"http://www.gallup.com/poll/166553/less-recommended-amount-sleep.aspx\">People are sleeping demonstrably less than they did 70 years ago\u003c/a>. An estimated 70 million Americans suffer from some form of chronic sleep disorder, and 40 percent get less than the recommended amount of sleep – seven and a half to eight hours a night.\u003c/p>\n\u003cp>Contributing factors include multi-tasking, the invasion of technology in the bedroom and long commute times, which rob us of precious free hours, Walker said. But the biggest culprit may be our own attitudes.\u003c/p>\n\u003cp>“I think where we’re at in modern-day society is a problematic relationship with sleep,” he said.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>“We know that sleep is fundamentally important at the most basic of biological levels,” he said. “But something strange has happened – sleep has received a stigma. There’s some kind of intonation which suggests that getting sufficient sleep is equivalent to being lazy. We wear this badge of sleep deprivation like some kind of honor emblem on our arm, and that’s profoundly misguided.”\u003c/p>\n\u003ch2>Additional Links\u003c/h2>\n\u003cul>\n\u003cli>\u003ca href=\"https://www.youtube.com/watch?v=yTIDkj9Tn58\">Watch the full episode of QUEST.\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201408261000\">Forum with Michael Krasny: sleep expert Matthew Walker\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://blogs.kqed.org/stateofhealth/2014/08/27/sleep-apps-myths-and-more-strategies-for-a-good-nights-rest/\">Sleep Apps, Myths and More: Strategies for a Good Night’s Rest\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201311270930\">Forum with Dave Iverson: sleep therapy as a treatment for depression\u003c/a>\u003c/li>\n\u003c/ul>\n\n","blocks":[],"excerpt":"Sleep: It’s more important than you might think. Watch the video to see how sleep imprints memories, regulates emotions, and cleanses the brain of toxins. ","status":"publish","parent":0,"modified":1442634965,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":21,"wordCount":1052},"headData":{"title":"Catching Up on Sleep Science | KQED","description":"Sleep: It’s more important than you might think. Watch the video to see how sleep imprints memories, regulates emotions, and cleanses the brain of toxins. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"17514 http://science.kqed.org/quest/video/catching-up-on-sleep-science/","disqusUrl":"https://ww2.kqed.org/quest/2014/11/12/catching-up-on-sleep-science/","disqusTitle":"Catching Up on Sleep Science","videoEmbed":"https://www.youtube.com/watch?v=HW1HxGJAjqY","source":"Health","sourceUrl":"http://ww2.kqed.org/quest/category/health/","path":"/quest/17514/catching-up-on-sleep-science","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cem>This video story was originally produced by \u003ca href=\"http://ww2.kqed.org/quest/author/sheraz-sadiq/\">Sheraz Sadiq\u003c/a> and was updated by\u003ca href=\"http://ww2.kqed.org/quest/author/lisalanders/\"> Lisa Landers\u003c/a> and \u003ca href=\"http://ww2.kqed.org/quest/author/acurry/\">Arwen Curry.\u003c/a>\u003c/em>\u003c/p>\n\u003cp>Be honest – do you ever brag about how little sleep you get? If so, you’re not alone. Humans are the only species that seems to deliberately deprive themselves of sleep. But if you’ve ever uttered a phrase like “I’ll sleep when I’m dead,” it’s time for a wake-up call, scientists say.\u003c/p>\n\u003cfigure id=\"attachment_72675\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear.jpg\">\u003cimg class=\"size-thumbnail wp-image-72675\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear-300x169.jpg\" alt=\"Sleep is common to all species that have been studied to date.\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Sleep is common to all species that have been studied to date.\u003c/figcaption>\u003c/figure>\n\u003cp>Researchers have long known that adequate sleep is critical for good health. Insufficient sleep \u003ca href=\"http://www.mayoclinic.org/diseases-conditions/insomnia/expert-answers/lack-of-sleep/faq-20057757\">impairs the immune system\u003c/a>, and is associated with everything from \u003ca href=\"http://www.hsph.harvard.edu/nutritionsource/sleep/\">obesity\u003c/a> to cardiovascular disease, stroke to cancer, depression to schizophrenia and \u003ca href=\"http://news.temple.edu/news/2014-03-18/chronic-sleep-disturbance-might-trigger-onset-alzheimer%E2%80%99s\">Alzheimer’s disease\u003c/a>. Now scientists are several steps closer to knowing how sleep keeps us healthy.\u003c/p>\n\u003cp>An important clue about sleep’s function surfaced in \u003ca href=\"http://www.nature.com/neuro/journal/v16/n2/full/nn.3303.html\">a 2013 study\u003c/a> published in the journal \u003cem>\u003ca href=\"http://www.nature.com/neuro/index.html\">Nature Neuroscience\u003c/a> \u003c/em>and conducted at the University of California-Berkeley. The study, by neuroscience professor Matthew Walker and his colleagues, showed that the structural changes the brain experiences as we age damage the quality of deep sleep. This hinders the brain’s ongoing ability to store memories.\u003c/p>\n\u003cfigure id=\"attachment_72671\" class=\"wp-caption alignleft\" style=\"max-width: 264px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800.jpg\">\u003cimg class=\"wp-image-72671 size-thumbnail\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800-264x169.jpg\" alt=\"Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley Photo by Arwen Curry.\" width=\"264\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley.\u003cbr> Photo by Arwen Curry.\u003c/figcaption>\u003c/figure>\n\u003cp>Scientists were already aware of a connection between sleep and memory – now they are developing a working hypothesis about how the mechanism actually works.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>“It’s almost as though your learning system is like a USB stick,” Walker said. “During the day you’re acquiring lots of information rapidly.” This information is lodged in an area of the brain called the hippocampus.\u003c/p>\n\u003cp>But when we sleep, this data is exported to “the hard drive of our brain,” a larger storage space called the cortex.\u003c/p>\n\u003cp>“When we wake up the next day, our USB stick has now been cleared out, so we can start to learn new information anew,” Walker said. “We’ve refreshed our learning capacity.”\u003c/p>\n\u003cp>The idea that we need less sleep as we age is a fallacy, he added. It now appears that the brain is physically unable to achieve the amount of slow-wave, non-rapid-eye-movement sleep needed to consolidate memories as we grow older. By the time we’re 50 years old, non-REM sleep has reduced by half compared to when we were 18 years old. By the time we’re 70, deep sleep is down to about 5 percent.\u003c/p>\n\u003cfigure id=\"attachment_72668\" class=\"wp-caption alignright\" style=\"max-width: 288px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\">\u003cimg class=\"wp-image-72668 size-full\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\" alt=\"Scientists use electric pulses to copy the rhythm of slow-wave sleep, which declines as we age.\" width=\"288\" height=\"162\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Scientists use electrical pulses to copy the rhythm of slow-wave sleep, which declines as we age.\u003c/figcaption>\u003c/figure>\n\u003cp>This research suggests that improving slow-wave sleep, which takes up about a quarter of the night, could slow the decline of memory as we age. Scientists are investigating \u003ca href=\"http://www.sciencedirect.com/science/article/pii/016643289390140L\">ways to use electrical stimulation to improve deep sleep in older people\u003c/a> by attaching electrodes to the scalp to create a mild current that mimics the pattern of slow-wave sleep.\u003c/p>\n\u003cp>The science of sleep has traditionally been abstract, but advances in imaging technology now allow scientists to peek inside the sleeping brain. In \u003ca href=\"http://www.urmc.rochester.edu/news/story/index.cfm?id=3956\">a groundbreaking 2013 study\u003c/a>, researchers at the University of Rochester Medical Center injected dyes into the brains of sleeping mice, and watched in real-time as the neurons in their brains shrank dramatically by about 60 percent. This increased the spaces between the brain cells, allowing cerebrospinal fluid to easily flow through and cleanse the brain of naturally occurring toxic waste.\u003c/p>\n\u003cfigure id=\"attachment_72672\" class=\"wp-caption alignleft\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800.jpg\">\u003cimg class=\"wp-image-72672 size-large\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800-640x360.jpg\" alt=\"This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse.\" width=\"640\" height=\"360\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse. Photo courtesy of the University of Rochester Medical Center.\u003c/figcaption>\u003c/figure>\n\u003cp>“It’s almost as though you’re sort of walking past one of those delightful posh hotels and during the day there’s lots of dirt that happens on the sidewalk,” said Walker. “And then at night, someone comes out with one of those pressure-jet washers and cleans it all out, so that it’s fresh and functional the next day. That’s exactly what we think is now happening during sleep at night.”\u003c/p>\n\u003cp>Of particular note is that chronic sleep deprivation contributes to \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/24887018\">the buildup of a toxic protein called beta-amyloid\u003c/a>, which is a predictor of Alzheimer’s disease.\u003c/p>\n\u003cp>Walker’s research also suggests strong connections between sleep and creativity and emotional regulation. But with all we’ve learned about sleep, there remains much more to be discovered.\u003c/p>\n\u003cp>“If you think about it,” said Walker, “we’ve understood the other three main biological drives – eating, drinking and reproducing – for many tens, if not hundreds, of years. But the fourth main biological drive, common across all species that we’ve studied, which is to sleep, remains that quintessential mystery.”\u003c/p>\n\u003cp>One thing is clear: \u003ca href=\"http://www.gallup.com/poll/166553/less-recommended-amount-sleep.aspx\">People are sleeping demonstrably less than they did 70 years ago\u003c/a>. An estimated 70 million Americans suffer from some form of chronic sleep disorder, and 40 percent get less than the recommended amount of sleep – seven and a half to eight hours a night.\u003c/p>\n\u003cp>Contributing factors include multi-tasking, the invasion of technology in the bedroom and long commute times, which rob us of precious free hours, Walker said. But the biggest culprit may be our own attitudes.\u003c/p>\n\u003cp>“I think where we’re at in modern-day society is a problematic relationship with sleep,” he said.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>“We know that sleep is fundamentally important at the most basic of biological levels,” he said. “But something strange has happened – sleep has received a stigma. There’s some kind of intonation which suggests that getting sufficient sleep is equivalent to being lazy. We wear this badge of sleep deprivation like some kind of honor emblem on our arm, and that’s profoundly misguided.”\u003c/p>\n\u003ch2>Additional Links\u003c/h2>\n\u003cul>\n\u003cli>\u003ca href=\"https://www.youtube.com/watch?v=yTIDkj9Tn58\">Watch the full episode of QUEST.\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201408261000\">Forum with Michael Krasny: sleep expert Matthew Walker\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://blogs.kqed.org/stateofhealth/2014/08/27/sleep-apps-myths-and-more-strategies-for-a-good-nights-rest/\">Sleep Apps, Myths and More: Strategies for a Good Night’s Rest\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201311270930\">Forum with Dave Iverson: sleep therapy as a treatment for depression\u003c/a>\u003c/li>\n\u003c/ul>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/17514/catching-up-on-sleep-science","authors":["6444"],"categories":["quest_4","quest_12"],"tags":["quest_83","quest_135","quest_13038","quest_13048","quest_13044","quest_423","quest_13042","quest_13045","quest_13047","quest_13052","quest_13050","quest_13040","quest_13046","quest_12269","quest_13201","quest_13035","quest_1451","quest_11723","quest_10537","quest_1788","quest_13039","quest_13036","quest_1916","quest_13041","quest_9816","quest_13037","quest_2031","quest_13","quest_10538","quest_2655","quest_13034","quest_13051","quest_2893","quest_3021","quest_12094","quest_13043","quest_3071","quest_13049"],"featImg":"quest_72659","label":"source_quest_17514"},"quest_28257":{"type":"posts","id":"quest_28257","meta":{"index":"posts_1591205157","site":"quest","id":"28257","score":null,"sort":[1323459513000]},"guestAuthors":[],"slug":"can-ptsd-nightmares-be-cured","title":"Can PTSD Nightmares Be Cured?","publishDate":1323459513,"format":"audio","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>http://www.kqed.org/.stream/anon/radio/quest/2011/12/2011-12-12-quest.mp3\u003c/p>\n\u003cfigure id=\"attachment_28265\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/12/Kreep_Bed_Flickr_REV.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/12/Kreep_Bed_Flickr_REV-300x169.jpg\" alt=\"\" title=\"Kreep_Bed_Flickr_REV\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-28265\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">In many PTSD patients, sleep problems such as insomnia and nightmares are the most common complaint. (Photo courtesy of Flickr user <a href=\"http://www.flickr.com/photos/kreep\" target=\"_blank\">Kreep</a>.)\u003c/figcaption>\u003c/figure>\n\u003cp>Sam Brace doesn’t want to talk about what he saw when he was a soldier in Iraq eight years ago. Brace is an inpatient at a PTSD treatment center run by the Department of Veterans Affairs in Menlo Park, and that trauma is something he’s actively trying not to dwell on. But what he can’t control are his dreams.\u003c/p>\n\u003cp>\"When I was overseas we hit an IED, um…\" he says, trailing off. \"When I have a nightmare normally it’s something related to that. \"\u003c/p>\n\u003cp>In the past, scientists who study PTSD thought of nightmares and insomnia as byproducts of the disorder, side effects that could only be targeted through daytime interventions, such as cognitive behavioral therapy. But that view is changing. \u003c/p>\n\u003cp>In Sam Brace and others afflicted with PTSD, nightmares and insomnia lead to alcoholism and drug abuse, and the inability to function well during the day. Doctors who treat PTSD say that sleep is central to the disorder, and that restoring it may go a long way toward helping patients return to normal lives.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\u003cstrong>\"Wacky\" dreams are healthy dreams\u003c/strong>\u003c/p>\n\u003cp>Steve Woodward, a psychiatrist with the National Center for PTSD in Menlo Park says the hallmark of a healthy dream is that it seems kind of random.\u003c/p>\n\u003cp>\"They’re wacky,\" says Woodward. \"They associate things that are not normally associated.\"\u003c/p>\n\u003cp>PTSD dreams, in contrast, are like a broken record: the same, real-life event, played over and over again. Woodward says he's seen patients haunted by the same true-to-life nightmare for twenty years.\u003c/p>\n\u003cp>The question scientists had was: why? Why can't people with PTSD sleep normally?\u003c/p>\n\u003cp>\u003cstrong>Healthy sleep as therapy\u003c/strong>\u003c/p>\n\u003cp>\u003ca href=\"http://walkerlab.berkeley.edu/people.html\">Matthew Walker\u003c/a> is a sleep researcher at the University of California, Berkeley. One of his particular interests is in rapid eye movement, or REM. It’s the stage of sleep where a lot of dreaming occurs.\u003c/p>\n\u003cp>REM sleep is also the only time of the day that the brain stops producing a kind of adrenaline called norepinephrine. That fact struck Walker as an intriguing mystery. Why would rapid eye movement sleep suppress this neurochemical, he wondered. Is there any function to that?\u003c/p>\n\u003cp>What Walker and his colleagues \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/22119526\">found\u003c/a> is that in healthy people, REM sleep is kind of like therapy. It's an adrenaline-free environment where the brain can process its memories while stripping away their sharp, emotional edges.\u003c/p>\n\u003cp>\"When you come back the next day,\" says Walker, \"yes, you can better recollect [the memory]. But also, it doesn’t trigger that same visceral reaction that you had at the time of learning.\"\u003c/p>\n\u003cp>Emotions are useful, says Walker, because they show us what really matters to us. But it's not useful to hold onto what he calls the \"emotional blanket,\" that accompanied the original event. The emotions, he says, \"have done their job. Now it’s time to hold on to the information of that memory, but let go of the emotion.\"\u003c/p>\n\u003cp>\u003cstrong>\"Broken\" REM sleep\u003c/strong>\u003c/p>\n\u003cp>Walker believes that in many people who have PTSD, REM sleep is broken. Something about PTSD either causes the brain to be overly sensitive to norepinephrine, or forces the brain to create too much of it. The brain's adrenaline system is effectively out of whack.\u003c/p>\n\u003cp>As a result, REM sleep is no longer theraputic. The PTSD brain can't process tough memories, so it just cycles through them, again and again.\u003c/p>\n\u003cp>Which begs a question: What if you could change that? What if you could make the adrenaline go away?\u003c/p>\n\u003cp>\u003cstrong>An old drug finds a new role\u003c/strong>\u003c/p>\n\u003cp>Murray Raskind directs Mental Health Services for the Department of Veterans Affairs Puget Sound Health Care System. About a decade ago, he became interested in a drug called Prazosin, which was traditionally used to treat high blood pressure.\u003c/p>\n\u003cp>Prazosin can be bought generically for about ten cents a pill. It can have the side effect of making people dizzy. For the most part, it's been supplanted by other, more recent hypertension drugs, whose effects last longer. But Prazosin turned out to have another use: It makes the PTSD brain less receptive to adrenaline.\u003c/p>\n\u003cp>As a result, as Raskind discovered, prazosin can change the way those patients dream.\u003c/p>\n\u003cp>Raskind tells the story of one of the first vets he ever treated with prazosin, a veteran Raskind calls Charles, who spent 13 months in a combat infantry unit in Vietnam.\u003c/p>\n\u003cp>What haunted Charles was one specific event from his service: Under an ambush by Vietcong forces, Charles and a fellow soldier, his closest friend, found themselves trapped in a landing zone in the jungle. Charles watched as his friend was killed by a mortar round. Fragments of the round pierced Charles' right knee, leaving him unable to run. Charles was saved at the last minute by troops in a Huey helicopter, just as Vietcong forces climbed through the wire to reach him.\u003c/p>\n\u003cp>\"This near-death experience,\" says Raskind, \"and even more distressing, the death of his best friend, whose death he felt he was unable to prevent, haunted him most nights, every week, year in and year out.\"\u003c/p>\n\u003cp>After a few weeks of Prazosin, Charles came in for a follow-up appointment. He told Raskind that he didn't think the drug was working. He was still dreaming, just about something else.\u003c/p>\n\u003cp>According to Raskind, the dream went like this: \"I'm in my fifth-grade classroom. And there’s a test, and if I don’t pass the test, I’m not gonna be promoted to the next grade. And I never even got the assignment!”\u003c/p>\n\u003cp>It was the stress dream, says Raskind, of a healthy brain, trying to work things out. \"I said 'Charles, that’s MY nightmare!'\" Raskind recalls.\u003c/p>\n\u003cp>So far the studies on prazosin have been small (abstracts can be found online, \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed?term=Thompson%20CE%2C%20Taylor%20FB%2C%20McFall%20ME%2C%20Barnes%20RF%2C%20Raskind%20MA\">here\u003c/a> and \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/20473055\">here\u003c/a> and \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/20726290\">here\u003c/a> – as well as of a 2008 round-up of data, \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/18387899\">here\u003c/a>) but promising in decreasing nightmares and helping people sleep longer.\u003c/p>\n\u003cp>Other small studies involving non-combat PTSD – people who had been victims of \u003ca href=\"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350188/?tool=pubmed\">crime and sexual assault\u003c/a>, as well as \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/19934720\">refugees\u003c/a> – found an improvement in the quality of their dreams, and overall sleep, as well.\u003c/p>\n\u003cp>The Department of Veterans Affairs is undergoing \u003ca href=\"http://www.research.va.gov/programs/csp/csp563.cfm\">its own study \u003c/a>on prazosin in PTSD, which is taking part in 13 medical centers across the country. But is already prescribing the drug to about 15 percent of its PTSD patients -- about 70,000 people.\u003c/p>\n\u003cp>Murray Raskind, for one, would like to see that number rise.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>\"For us,\" he says, \"it's a simple thing that works.\"\u003c/p>\n\n","blocks":[],"excerpt":"The hallmark of a healthy dream is its weirdness. PTSD dreams, in contrast, are like a broken record, the same, real-life event, played over and over again, in some patients, for decades. ","status":"publish","parent":0,"modified":1370996846,"stats":{"hasAudio":true,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":36,"wordCount":1166},"headData":{"title":"Can PTSD Nightmares Be Cured? | KQED","description":"The hallmark of a healthy dream is its weirdness. PTSD dreams, in contrast, are like a broken record, the same, real-life event, played over and over again, in some patients, for decades. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"disqusIdentifier":"28257 http://science.kqed.org/quest/?post_type=audio_reports&p=28257","disqusUrl":"https://ww2.kqed.org/quest/2011/12/09/can-ptsd-nightmares-be-cured/","disqusTitle":"Can PTSD Nightmares Be Cured?","path":"/quest/28257/can-ptsd-nightmares-be-cured","audioUrl":"http://www.kqed.org/.stream/anon/radio/quest/2011/12/2011-12-12-quest.mp3","audioDuration":null,"audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>http://www.kqed.org/.stream/anon/radio/quest/2011/12/2011-12-12-quest.mp3\u003c/p>\n\u003cfigure id=\"attachment_28265\" class=\"wp-caption alignleft\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/12/Kreep_Bed_Flickr_REV.jpg\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/12/Kreep_Bed_Flickr_REV-300x169.jpg\" alt=\"\" title=\"Kreep_Bed_Flickr_REV\" width=\"300\" height=\"169\" class=\"size-thumbnail wp-image-28265\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">In many PTSD patients, sleep problems such as insomnia and nightmares are the most common complaint. (Photo courtesy of Flickr user <a href=\"http://www.flickr.com/photos/kreep\" target=\"_blank\">Kreep</a>.)\u003c/figcaption>\u003c/figure>\n\u003cp>Sam Brace doesn’t want to talk about what he saw when he was a soldier in Iraq eight years ago. Brace is an inpatient at a PTSD treatment center run by the Department of Veterans Affairs in Menlo Park, and that trauma is something he’s actively trying not to dwell on. But what he can’t control are his dreams.\u003c/p>\n\u003cp>\"When I was overseas we hit an IED, um…\" he says, trailing off. \"When I have a nightmare normally it’s something related to that. \"\u003c/p>\n\u003cp>In the past, scientists who study PTSD thought of nightmares and insomnia as byproducts of the disorder, side effects that could only be targeted through daytime interventions, such as cognitive behavioral therapy. But that view is changing. \u003c/p>\n\u003cp>In Sam Brace and others afflicted with PTSD, nightmares and insomnia lead to alcoholism and drug abuse, and the inability to function well during the day. Doctors who treat PTSD say that sleep is central to the disorder, and that restoring it may go a long way toward helping patients return to normal lives.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cstrong>\"Wacky\" dreams are healthy dreams\u003c/strong>\u003c/p>\n\u003cp>Steve Woodward, a psychiatrist with the National Center for PTSD in Menlo Park says the hallmark of a healthy dream is that it seems kind of random.\u003c/p>\n\u003cp>\"They’re wacky,\" says Woodward. \"They associate things that are not normally associated.\"\u003c/p>\n\u003cp>PTSD dreams, in contrast, are like a broken record: the same, real-life event, played over and over again. Woodward says he's seen patients haunted by the same true-to-life nightmare for twenty years.\u003c/p>\n\u003cp>The question scientists had was: why? Why can't people with PTSD sleep normally?\u003c/p>\n\u003cp>\u003cstrong>Healthy sleep as therapy\u003c/strong>\u003c/p>\n\u003cp>\u003ca href=\"http://walkerlab.berkeley.edu/people.html\">Matthew Walker\u003c/a> is a sleep researcher at the University of California, Berkeley. One of his particular interests is in rapid eye movement, or REM. It’s the stage of sleep where a lot of dreaming occurs.\u003c/p>\n\u003cp>REM sleep is also the only time of the day that the brain stops producing a kind of adrenaline called norepinephrine. That fact struck Walker as an intriguing mystery. Why would rapid eye movement sleep suppress this neurochemical, he wondered. Is there any function to that?\u003c/p>\n\u003cp>What Walker and his colleagues \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/22119526\">found\u003c/a> is that in healthy people, REM sleep is kind of like therapy. It's an adrenaline-free environment where the brain can process its memories while stripping away their sharp, emotional edges.\u003c/p>\n\u003cp>\"When you come back the next day,\" says Walker, \"yes, you can better recollect [the memory]. But also, it doesn’t trigger that same visceral reaction that you had at the time of learning.\"\u003c/p>\n\u003cp>Emotions are useful, says Walker, because they show us what really matters to us. But it's not useful to hold onto what he calls the \"emotional blanket,\" that accompanied the original event. The emotions, he says, \"have done their job. Now it’s time to hold on to the information of that memory, but let go of the emotion.\"\u003c/p>\n\u003cp>\u003cstrong>\"Broken\" REM sleep\u003c/strong>\u003c/p>\n\u003cp>Walker believes that in many people who have PTSD, REM sleep is broken. Something about PTSD either causes the brain to be overly sensitive to norepinephrine, or forces the brain to create too much of it. The brain's adrenaline system is effectively out of whack.\u003c/p>\n\u003cp>As a result, REM sleep is no longer theraputic. The PTSD brain can't process tough memories, so it just cycles through them, again and again.\u003c/p>\n\u003cp>Which begs a question: What if you could change that? What if you could make the adrenaline go away?\u003c/p>\n\u003cp>\u003cstrong>An old drug finds a new role\u003c/strong>\u003c/p>\n\u003cp>Murray Raskind directs Mental Health Services for the Department of Veterans Affairs Puget Sound Health Care System. About a decade ago, he became interested in a drug called Prazosin, which was traditionally used to treat high blood pressure.\u003c/p>\n\u003cp>Prazosin can be bought generically for about ten cents a pill. It can have the side effect of making people dizzy. For the most part, it's been supplanted by other, more recent hypertension drugs, whose effects last longer. But Prazosin turned out to have another use: It makes the PTSD brain less receptive to adrenaline.\u003c/p>\n\u003cp>As a result, as Raskind discovered, prazosin can change the way those patients dream.\u003c/p>\n\u003cp>Raskind tells the story of one of the first vets he ever treated with prazosin, a veteran Raskind calls Charles, who spent 13 months in a combat infantry unit in Vietnam.\u003c/p>\n\u003cp>What haunted Charles was one specific event from his service: Under an ambush by Vietcong forces, Charles and a fellow soldier, his closest friend, found themselves trapped in a landing zone in the jungle. Charles watched as his friend was killed by a mortar round. Fragments of the round pierced Charles' right knee, leaving him unable to run. Charles was saved at the last minute by troops in a Huey helicopter, just as Vietcong forces climbed through the wire to reach him.\u003c/p>\n\u003cp>\"This near-death experience,\" says Raskind, \"and even more distressing, the death of his best friend, whose death he felt he was unable to prevent, haunted him most nights, every week, year in and year out.\"\u003c/p>\n\u003cp>After a few weeks of Prazosin, Charles came in for a follow-up appointment. He told Raskind that he didn't think the drug was working. He was still dreaming, just about something else.\u003c/p>\n\u003cp>According to Raskind, the dream went like this: \"I'm in my fifth-grade classroom. And there’s a test, and if I don’t pass the test, I’m not gonna be promoted to the next grade. And I never even got the assignment!”\u003c/p>\n\u003cp>It was the stress dream, says Raskind, of a healthy brain, trying to work things out. \"I said 'Charles, that’s MY nightmare!'\" Raskind recalls.\u003c/p>\n\u003cp>So far the studies on prazosin have been small (abstracts can be found online, \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed?term=Thompson%20CE%2C%20Taylor%20FB%2C%20McFall%20ME%2C%20Barnes%20RF%2C%20Raskind%20MA\">here\u003c/a> and \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/20473055\">here\u003c/a> and \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/20726290\">here\u003c/a> – as well as of a 2008 round-up of data, \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/18387899\">here\u003c/a>) but promising in decreasing nightmares and helping people sleep longer.\u003c/p>\n\u003cp>Other small studies involving non-combat PTSD – people who had been victims of \u003ca href=\"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350188/?tool=pubmed\">crime and sexual assault\u003c/a>, as well as \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/19934720\">refugees\u003c/a> – found an improvement in the quality of their dreams, and overall sleep, as well.\u003c/p>\n\u003cp>The Department of Veterans Affairs is undergoing \u003ca href=\"http://www.research.va.gov/programs/csp/csp563.cfm\">its own study \u003c/a>on prazosin in PTSD, which is taking part in 13 medical centers across the country. But is already prescribing the drug to about 15 percent of its PTSD patients -- about 70,000 people.\u003c/p>\n\u003cp>Murray Raskind, for one, would like to see that number rise.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\"For us,\" he says, \"it's a simple thing that works.\"\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/28257/can-ptsd-nightmares-be-cured","authors":["210"],"categories":["quest_12"],"tags":["quest_252","quest_22","quest_10537","quest_10536","quest_13203","quest_10532","quest_10533","quest_2328","quest_13202","quest_10538","quest_10535","quest_2655","quest_10534","quest_10531"],"label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. Michel Martin hosts on the weekends.","airtime":"MON-FRI 1pm-2pm, 4:30pm-6:30pm\u003cbr />SAT-SUN 5pm-6pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/All-Things-Considered-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/all-things-considered/","meta":{"site":"news","source":"npr"},"link":"/radio/program/all-things-considered"},"american-suburb-podcast":{"id":"american-suburb-podcast","title":"American Suburb: The Podcast","tagline":"The flip side of gentrification, told through one town","info":"Gentrification is changing cities across America, forcing people from neighborhoods they have long called home. Call them the displaced. Now those priced out of the Bay Area are looking for a better life in an unlikely place. American Suburb follows this migration to one California town along the Delta, 45 miles from San Francisco. But is this once sleepy suburb ready for them?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/American-Suburb-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/news/series/american-suburb-podcast","meta":{"site":"news","source":"kqed","order":"13"},"link":"/news/series/american-suburb-podcast/","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=1287748328","tuneIn":"https://tunein.com/radio/American-Suburb-p1086805/","rss":"https://ww2.kqed.org/news/series/american-suburb-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMzMDExODgxNjA5"}},"baycurious":{"id":"baycurious","title":"Bay Curious","tagline":"Exploring the Bay Area, one question at a time","info":"KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.","airtime":"THU 10pm, FRI 1am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.commonwealthclub.org/podcasts","meta":{"site":"news","source":"Commonwealth Club of California"},"link":"/radio/program/commonwealth-club","subscribe":{"apple":"https://itunes.apple.com/us/podcast/commonwealth-club-of-california-podcast/id976334034?mt=2","google":"https://podcasts.google.com/feed/aHR0cDovL3d3dy5jb21tb253ZWFsdGhjbHViLm9yZy9hdWRpby9wb2RjYXN0L3dlZWtseS54bWw","tuneIn":"https://tunein.com/radio/Commonwealth-Club-of-California-p1060/"}},"considerthis":{"id":"considerthis","title":"Consider This","tagline":"Make sense of the day","info":"Make sense of the day. Every weekday afternoon, Consider This helps you consider the major stories of the day in less than 15 minutes, featuring the reporting and storytelling resources of NPR. Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Consider-This-Podcast-Tile-703x703-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. It is produced in partnership with WNYC.","imageSrc":"https://ww2.kqed.org/news/wp-content/uploads/sites/10/2018/05/freakonomicsRadio.png","officialWebsiteLink":"http://freakonomics.com/","airtime":"SUN 1am-2am, SAT 3pm-4pm","meta":{"site":"radio","source":"WNYC"},"link":"/radio/program/freakonomics-radio","subscribe":{"npr":"https://rpb3r.app.goo.gl/4s8b","apple":"https://itunes.apple.com/us/podcast/freakonomics-radio/id354668519","tuneIn":"https://tunein.com/podcasts/WNYC-Podcasts/Freakonomics-Radio-p272293/","rss":"https://feeds.feedburner.com/freakonomicsradio"}},"fresh-air":{"id":"fresh-air","title":"Fresh Air","info":"Hosted by Terry Gross, \u003cem>Fresh Air from WHYY\u003c/em> is the Peabody Award-winning weekday magazine of contemporary arts and issues. One of public radio's most popular programs, Fresh Air features intimate conversations with today's biggest luminaries.","airtime":"MON-FRI 7pm-8pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Fresh-Air-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/fresh-air/","meta":{"site":"radio","source":"npr"},"link":"/radio/program/fresh-air","subscribe":{"npr":"https://rpb3r.app.goo.gl/4s8b","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=214089682&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Fresh-Air-p17/","rss":"https://feeds.npr.org/381444908/podcast.xml"}},"here-and-now":{"id":"here-and-now","title":"Here & Now","info":"A live production of NPR and WBUR Boston, in collaboration with stations across the country, Here & Now reflects the fluid world of news as it's happening in the middle of the day, with timely, in-depth news, interviews and conversation. Hosted by Robin Young, Jeremy Hobson and Tonya Mosley.","airtime":"MON-THU 11am-12pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Here-And-Now-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://www.wbur.org/hereandnow","meta":{"site":"news","source":"npr"},"link":"/radio/program/here-and-now","subsdcribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=426698661","tuneIn":"https://tunein.com/radio/Here--Now-p211/","rss":"https://feeds.npr.org/510051/podcast.xml"}},"how-i-built-this":{"id":"how-i-built-this","title":"How I Built This with Guy Raz","info":"Guy Raz dives into the stories behind some of the world's best known companies. 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No other part of the globe has experienced such dynamic political and social change in recent years.","airtime":"SAT 3am-4am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Inside-Europe-Podcast-Tile-300x300-1.jpg","meta":{"site":"news","source":"Deutsche Welle"},"link":"/radio/program/inside-europe","subscribe":{"apple":"https://itunes.apple.com/us/podcast/inside-europe/id80106806?mt=2","tuneIn":"https://tunein.com/radio/Inside-Europe-p731/","rss":"https://partner.dw.com/xml/podcast_inside-europe"}},"latino-usa":{"id":"latino-usa","title":"Latino USA","airtime":"MON 1am-2am, SUN 6pm-7pm","info":"Latino USA, the radio journal of news and culture, is the only national, English-language radio program produced from a Latino perspective.","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/latinoUsa.jpg","officialWebsiteLink":"http://latinousa.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/latino-usa","subscribe":{"npr":"https://rpb3r.app.goo.gl/xtTd","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=79681317&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Latino-USA-p621/","rss":"https://feeds.npr.org/510016/podcast.xml"}},"live-from-here-highlights":{"id":"live-from-here-highlights","title":"Live from Here Highlights","info":"Chris Thile steps to the mic as the host of Live from Here (formerly A Prairie Home Companion), a live public radio variety show. Download Chris’s Song of the Week plus other highlights from the broadcast. Produced by American Public Media.","airtime":"SAT 6pm-8pm, SUN 11am-1pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Live-From-Here-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.livefromhere.org/","meta":{"site":"arts","source":"american public media"},"link":"/radio/program/live-from-here-highlights","subscribe":{"apple":"https://itunes.apple.com/us/podcast/id1167173941","tuneIn":"https://tunein.com/radio/Live-from-Here-Highlights-p921744/","rss":"https://feeds.publicradio.org/public_feeds/a-prairie-home-companion-highlights/rss/rss"}},"marketplace":{"id":"marketplace","title":"Marketplace","info":"Our flagship program, helmed by Kai Ryssdal, examines what the day in money delivered, through stories, conversations, newsworthy numbers and more. 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