Producer's Notes: In Search of a Better Night's Sleep
Producer's Notes: The Sweet Science of Chocolate
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In addition to producing television content for KQED Science, he has also created online features and written news articles on scientific subjects ranging from astronomy to synthetic biology.","avatar":"https://secure.gravatar.com/avatar/9731b29e144af1965b0b7eaa56555561?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"arts","roles":["editor"]},{"site":"quest","roles":["leadcoordinator","editor"]}],"headData":{"title":"Sheraz Sadiq | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/9731b29e144af1965b0b7eaa56555561?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/9731b29e144af1965b0b7eaa56555561?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/sheraz-sadiq"},"acurry":{"type":"authors","id":"6444","meta":{"index":"authors_1591205172","id":"6444","found":true},"name":"Arwen Curry","firstName":"Arwen","lastName":"Curry","slug":"acurry","email":"acurry@KQED.org","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Arwen Curry is Associate Producer of TV at KQED Science. She comes to KQED from documentary film, and is director of \u003cem>Worlds of Ursula K. Le Guin\u003c/em>, a feature documentary about the influential science fiction writer. She was Associate Producer of the films \u003cem>Regarding Susan Sontag\u003c/em>, \u003cem>American Jerusalem: Jews and the Making of San Francisco\u003c/em>, \u003cem>EAMES: The Architect & The Painter\u003c/em>, \u003cem>Utopia in Four Movements\u003c/em>, and co-produced and directed \u003cem>Stuffed\u003c/em>, a short film about compulsive hoarding. Arwen was editor of the punk magazine \u003cem>Maximum Rock 'n' Roll\u003c/em>, and has been a contributor to Radio Lab and McSweeney’s. She is a Bay Area native and a graduate of the UC Berkeley Graduate School of Journalism.","avatar":"https://secure.gravatar.com/avatar/59af0722ca76a9bcd9dd6da80e683e18?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"science","roles":["editor"]},{"site":"quest","roles":["leadcoordinator","subscriber"]}],"headData":{"title":"Arwen Curry | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/59af0722ca76a9bcd9dd6da80e683e18?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/59af0722ca76a9bcd9dd6da80e683e18?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/acurry"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"home","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"quest_17514":{"type":"posts","id":"quest_17514","meta":{"index":"posts_1591205157","site":"quest","id":"17514","score":null,"sort":[1415804432000]},"guestAuthors":[],"slug":"catching-up-on-sleep-science","title":"Catching Up on Sleep Science","publishDate":1415804432,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{},"content":"\u003cp>\u003cem>This video story was originally produced by \u003ca href=\"http://ww2.kqed.org/quest/author/sheraz-sadiq/\">Sheraz Sadiq\u003c/a> and was updated by\u003ca href=\"http://ww2.kqed.org/quest/author/lisalanders/\"> Lisa Landers\u003c/a> and \u003ca href=\"http://ww2.kqed.org/quest/author/acurry/\">Arwen Curry.\u003c/a>\u003c/em>\u003c/p>\n\u003cp>Be honest – do you ever brag about how little sleep you get? If so, you’re not alone. Humans are the only species that seems to deliberately deprive themselves of sleep. But if you’ve ever uttered a phrase like “I’ll sleep when I’m dead,” it’s time for a wake-up call, scientists say.\u003c/p>\n\u003cfigure id=\"attachment_72675\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear.jpg\">\u003cimg class=\"size-thumbnail wp-image-72675\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear-300x169.jpg\" alt=\"Sleep is common to all species that have been studied to date.\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Sleep is common to all species that have been studied to date.\u003c/figcaption>\u003c/figure>\n\u003cp>Researchers have long known that adequate sleep is critical for good health. Insufficient sleep \u003ca href=\"http://www.mayoclinic.org/diseases-conditions/insomnia/expert-answers/lack-of-sleep/faq-20057757\">impairs the immune system\u003c/a>, and is associated with everything from \u003ca href=\"http://www.hsph.harvard.edu/nutritionsource/sleep/\">obesity\u003c/a> to cardiovascular disease, stroke to cancer, depression to schizophrenia and \u003ca href=\"http://news.temple.edu/news/2014-03-18/chronic-sleep-disturbance-might-trigger-onset-alzheimer%E2%80%99s\">Alzheimer’s disease\u003c/a>. Now scientists are several steps closer to knowing how sleep keeps us healthy.\u003c/p>\n\u003cp>An important clue about sleep’s function surfaced in \u003ca href=\"http://www.nature.com/neuro/journal/v16/n2/full/nn.3303.html\">a 2013 study\u003c/a> published in the journal \u003cem>\u003ca href=\"http://www.nature.com/neuro/index.html\">Nature Neuroscience\u003c/a> \u003c/em>and conducted at the University of California-Berkeley. The study, by neuroscience professor Matthew Walker and his colleagues, showed that the structural changes the brain experiences as we age damage the quality of deep sleep. This hinders the brain’s ongoing ability to store memories.\u003c/p>\n\u003cfigure id=\"attachment_72671\" class=\"wp-caption alignleft\" style=\"max-width: 264px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800.jpg\">\u003cimg class=\"wp-image-72671 size-thumbnail\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800-264x169.jpg\" alt=\"Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley Photo by Arwen Curry.\" width=\"264\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley.\u003cbr> Photo by Arwen Curry.\u003c/figcaption>\u003c/figure>\n\u003cp>Scientists were already aware of a connection between sleep and memory – now they are developing a working hypothesis about how the mechanism actually works.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>“It’s almost as though your learning system is like a USB stick,” Walker said. “During the day you’re acquiring lots of information rapidly.” This information is lodged in an area of the brain called the hippocampus.\u003c/p>\n\u003cp>But when we sleep, this data is exported to “the hard drive of our brain,” a larger storage space called the cortex.\u003c/p>\n\u003cp>“When we wake up the next day, our USB stick has now been cleared out, so we can start to learn new information anew,” Walker said. “We’ve refreshed our learning capacity.”\u003c/p>\n\u003cp>The idea that we need less sleep as we age is a fallacy, he added. It now appears that the brain is physically unable to achieve the amount of slow-wave, non-rapid-eye-movement sleep needed to consolidate memories as we grow older. By the time we’re 50 years old, non-REM sleep has reduced by half compared to when we were 18 years old. By the time we’re 70, deep sleep is down to about 5 percent.\u003c/p>\n\u003cfigure id=\"attachment_72668\" class=\"wp-caption alignright\" style=\"max-width: 288px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\">\u003cimg class=\"wp-image-72668 size-full\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\" alt=\"Scientists use electric pulses to copy the rhythm of slow-wave sleep, which declines as we age.\" width=\"288\" height=\"162\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Scientists use electrical pulses to copy the rhythm of slow-wave sleep, which declines as we age.\u003c/figcaption>\u003c/figure>\n\u003cp>This research suggests that improving slow-wave sleep, which takes up about a quarter of the night, could slow the decline of memory as we age. Scientists are investigating \u003ca href=\"http://www.sciencedirect.com/science/article/pii/016643289390140L\">ways to use electrical stimulation to improve deep sleep in older people\u003c/a> by attaching electrodes to the scalp to create a mild current that mimics the pattern of slow-wave sleep.\u003c/p>\n\u003cp>The science of sleep has traditionally been abstract, but advances in imaging technology now allow scientists to peek inside the sleeping brain. In \u003ca href=\"http://www.urmc.rochester.edu/news/story/index.cfm?id=3956\">a groundbreaking 2013 study\u003c/a>, researchers at the University of Rochester Medical Center injected dyes into the brains of sleeping mice, and watched in real-time as the neurons in their brains shrank dramatically by about 60 percent. This increased the spaces between the brain cells, allowing cerebrospinal fluid to easily flow through and cleanse the brain of naturally occurring toxic waste.\u003c/p>\n\u003cfigure id=\"attachment_72672\" class=\"wp-caption alignleft\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800.jpg\">\u003cimg class=\"wp-image-72672 size-large\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800-640x360.jpg\" alt=\"This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse.\" width=\"640\" height=\"360\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse. Photo courtesy of the University of Rochester Medical Center.\u003c/figcaption>\u003c/figure>\n\u003cp>“It’s almost as though you’re sort of walking past one of those delightful posh hotels and during the day there’s lots of dirt that happens on the sidewalk,” said Walker. “And then at night, someone comes out with one of those pressure-jet washers and cleans it all out, so that it’s fresh and functional the next day. That’s exactly what we think is now happening during sleep at night.”\u003c/p>\n\u003cp>Of particular note is that chronic sleep deprivation contributes to \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/24887018\">the buildup of a toxic protein called beta-amyloid\u003c/a>, which is a predictor of Alzheimer’s disease.\u003c/p>\n\u003cp>Walker’s research also suggests strong connections between sleep and creativity and emotional regulation. But with all we’ve learned about sleep, there remains much more to be discovered.\u003c/p>\n\u003cp>“If you think about it,” said Walker, “we’ve understood the other three main biological drives – eating, drinking and reproducing – for many tens, if not hundreds, of years. But the fourth main biological drive, common across all species that we’ve studied, which is to sleep, remains that quintessential mystery.”\u003c/p>\n\u003cp>One thing is clear: \u003ca href=\"http://www.gallup.com/poll/166553/less-recommended-amount-sleep.aspx\">People are sleeping demonstrably less than they did 70 years ago\u003c/a>. An estimated 70 million Americans suffer from some form of chronic sleep disorder, and 40 percent get less than the recommended amount of sleep – seven and a half to eight hours a night.\u003c/p>\n\u003cp>Contributing factors include multi-tasking, the invasion of technology in the bedroom and long commute times, which rob us of precious free hours, Walker said. But the biggest culprit may be our own attitudes.\u003c/p>\n\u003cp>“I think where we’re at in modern-day society is a problematic relationship with sleep,” he said.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>“We know that sleep is fundamentally important at the most basic of biological levels,” he said. “But something strange has happened – sleep has received a stigma. There’s some kind of intonation which suggests that getting sufficient sleep is equivalent to being lazy. We wear this badge of sleep deprivation like some kind of honor emblem on our arm, and that’s profoundly misguided.”\u003c/p>\n\u003ch2>Additional Links\u003c/h2>\n\u003cul>\n\u003cli>\u003ca href=\"https://www.youtube.com/watch?v=yTIDkj9Tn58\">Watch the full episode of QUEST.\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201408261000\">Forum with Michael Krasny: sleep expert Matthew Walker\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://blogs.kqed.org/stateofhealth/2014/08/27/sleep-apps-myths-and-more-strategies-for-a-good-nights-rest/\">Sleep Apps, Myths and More: Strategies for a Good Night’s Rest\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201311270930\">Forum with Dave Iverson: sleep therapy as a treatment for depression\u003c/a>\u003c/li>\n\u003c/ul>\n\n","blocks":[],"excerpt":"Sleep: It’s more important than you might think. Watch the video to see how sleep imprints memories, regulates emotions, and cleanses the brain of toxins. ","status":"publish","parent":0,"modified":1442634965,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":21,"wordCount":1052},"headData":{"title":"Catching Up on Sleep Science | KQED","description":"Sleep: It’s more important than you might think. Watch the video to see how sleep imprints memories, regulates emotions, and cleanses the brain of toxins. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Catching Up on Sleep Science","datePublished":"2014-11-12T15:00:32.000Z","dateModified":"2015-09-19T03:56:05.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"17514 http://science.kqed.org/quest/video/catching-up-on-sleep-science/","disqusUrl":"https://ww2.kqed.org/quest/2014/11/12/catching-up-on-sleep-science/","disqusTitle":"Catching Up on Sleep Science","videoEmbed":"https://www.youtube.com/watch?v=HW1HxGJAjqY","source":"Health","sourceUrl":"http://ww2.kqed.org/quest/category/health/","path":"/quest/17514/catching-up-on-sleep-science","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cem>This video story was originally produced by \u003ca href=\"http://ww2.kqed.org/quest/author/sheraz-sadiq/\">Sheraz Sadiq\u003c/a> and was updated by\u003ca href=\"http://ww2.kqed.org/quest/author/lisalanders/\"> Lisa Landers\u003c/a> and \u003ca href=\"http://ww2.kqed.org/quest/author/acurry/\">Arwen Curry.\u003c/a>\u003c/em>\u003c/p>\n\u003cp>Be honest – do you ever brag about how little sleep you get? If so, you’re not alone. Humans are the only species that seems to deliberately deprive themselves of sleep. But if you’ve ever uttered a phrase like “I’ll sleep when I’m dead,” it’s time for a wake-up call, scientists say.\u003c/p>\n\u003cfigure id=\"attachment_72675\" class=\"wp-caption alignright\" style=\"max-width: 300px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear.jpg\">\u003cimg class=\"size-thumbnail wp-image-72675\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/803_SLEEP_polar_bear-300x169.jpg\" alt=\"Sleep is common to all species that have been studied to date.\" width=\"300\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Sleep is common to all species that have been studied to date.\u003c/figcaption>\u003c/figure>\n\u003cp>Researchers have long known that adequate sleep is critical for good health. Insufficient sleep \u003ca href=\"http://www.mayoclinic.org/diseases-conditions/insomnia/expert-answers/lack-of-sleep/faq-20057757\">impairs the immune system\u003c/a>, and is associated with everything from \u003ca href=\"http://www.hsph.harvard.edu/nutritionsource/sleep/\">obesity\u003c/a> to cardiovascular disease, stroke to cancer, depression to schizophrenia and \u003ca href=\"http://news.temple.edu/news/2014-03-18/chronic-sleep-disturbance-might-trigger-onset-alzheimer%E2%80%99s\">Alzheimer’s disease\u003c/a>. Now scientists are several steps closer to knowing how sleep keeps us healthy.\u003c/p>\n\u003cp>An important clue about sleep’s function surfaced in \u003ca href=\"http://www.nature.com/neuro/journal/v16/n2/full/nn.3303.html\">a 2013 study\u003c/a> published in the journal \u003cem>\u003ca href=\"http://www.nature.com/neuro/index.html\">Nature Neuroscience\u003c/a> \u003c/em>and conducted at the University of California-Berkeley. The study, by neuroscience professor Matthew Walker and his colleagues, showed that the structural changes the brain experiences as we age damage the quality of deep sleep. This hinders the brain’s ongoing ability to store memories.\u003c/p>\n\u003cfigure id=\"attachment_72671\" class=\"wp-caption alignleft\" style=\"max-width: 264px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800.jpg\">\u003cimg class=\"wp-image-72671 size-thumbnail\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Matthew_Walker_AC_800-264x169.jpg\" alt=\"Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley Photo by Arwen Curry.\" width=\"264\" height=\"169\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Professor Matthew Walker runs the Sleep and Neuroimaging Lab at the University of California-Berkeley.\u003cbr> Photo by Arwen Curry.\u003c/figcaption>\u003c/figure>\n\u003cp>Scientists were already aware of a connection between sleep and memory – now they are developing a working hypothesis about how the mechanism actually works.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>“It’s almost as though your learning system is like a USB stick,” Walker said. “During the day you’re acquiring lots of information rapidly.” This information is lodged in an area of the brain called the hippocampus.\u003c/p>\n\u003cp>But when we sleep, this data is exported to “the hard drive of our brain,” a larger storage space called the cortex.\u003c/p>\n\u003cp>“When we wake up the next day, our USB stick has now been cleared out, so we can start to learn new information anew,” Walker said. “We’ve refreshed our learning capacity.”\u003c/p>\n\u003cp>The idea that we need less sleep as we age is a fallacy, he added. It now appears that the brain is physically unable to achieve the amount of slow-wave, non-rapid-eye-movement sleep needed to consolidate memories as we grow older. By the time we’re 50 years old, non-REM sleep has reduced by half compared to when we were 18 years old. By the time we’re 70, deep sleep is down to about 5 percent.\u003c/p>\n\u003cfigure id=\"attachment_72668\" class=\"wp-caption alignright\" style=\"max-width: 288px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\">\u003cimg class=\"wp-image-72668 size-full\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/402a_sleep_640-288x162.jpg\" alt=\"Scientists use electric pulses to copy the rhythm of slow-wave sleep, which declines as we age.\" width=\"288\" height=\"162\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Scientists use electrical pulses to copy the rhythm of slow-wave sleep, which declines as we age.\u003c/figcaption>\u003c/figure>\n\u003cp>This research suggests that improving slow-wave sleep, which takes up about a quarter of the night, could slow the decline of memory as we age. Scientists are investigating \u003ca href=\"http://www.sciencedirect.com/science/article/pii/016643289390140L\">ways to use electrical stimulation to improve deep sleep in older people\u003c/a> by attaching electrodes to the scalp to create a mild current that mimics the pattern of slow-wave sleep.\u003c/p>\n\u003cp>The science of sleep has traditionally been abstract, but advances in imaging technology now allow scientists to peek inside the sleeping brain. In \u003ca href=\"http://www.urmc.rochester.edu/news/story/index.cfm?id=3956\">a groundbreaking 2013 study\u003c/a>, researchers at the University of Rochester Medical Center injected dyes into the brains of sleeping mice, and watched in real-time as the neurons in their brains shrank dramatically by about 60 percent. This increased the spaces between the brain cells, allowing cerebrospinal fluid to easily flow through and cleanse the brain of naturally occurring toxic waste.\u003c/p>\n\u003cfigure id=\"attachment_72672\" class=\"wp-caption alignleft\" style=\"max-width: 640px\">\u003ca href=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800.jpg\">\u003cimg class=\"wp-image-72672 size-large\" src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2014/10/Rochester_Brain_Flushing_800-640x360.jpg\" alt=\"This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse.\" width=\"640\" height=\"360\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">This photograph shows cerebrospinal fluid (in blue) rinsing toxins from the brain of a sleeping mouse. Photo courtesy of the University of Rochester Medical Center.\u003c/figcaption>\u003c/figure>\n\u003cp>“It’s almost as though you’re sort of walking past one of those delightful posh hotels and during the day there’s lots of dirt that happens on the sidewalk,” said Walker. “And then at night, someone comes out with one of those pressure-jet washers and cleans it all out, so that it’s fresh and functional the next day. That’s exactly what we think is now happening during sleep at night.”\u003c/p>\n\u003cp>Of particular note is that chronic sleep deprivation contributes to \u003ca href=\"http://www.ncbi.nlm.nih.gov/pubmed/24887018\">the buildup of a toxic protein called beta-amyloid\u003c/a>, which is a predictor of Alzheimer’s disease.\u003c/p>\n\u003cp>Walker’s research also suggests strong connections between sleep and creativity and emotional regulation. But with all we’ve learned about sleep, there remains much more to be discovered.\u003c/p>\n\u003cp>“If you think about it,” said Walker, “we’ve understood the other three main biological drives – eating, drinking and reproducing – for many tens, if not hundreds, of years. But the fourth main biological drive, common across all species that we’ve studied, which is to sleep, remains that quintessential mystery.”\u003c/p>\n\u003cp>One thing is clear: \u003ca href=\"http://www.gallup.com/poll/166553/less-recommended-amount-sleep.aspx\">People are sleeping demonstrably less than they did 70 years ago\u003c/a>. An estimated 70 million Americans suffer from some form of chronic sleep disorder, and 40 percent get less than the recommended amount of sleep – seven and a half to eight hours a night.\u003c/p>\n\u003cp>Contributing factors include multi-tasking, the invasion of technology in the bedroom and long commute times, which rob us of precious free hours, Walker said. But the biggest culprit may be our own attitudes.\u003c/p>\n\u003cp>“I think where we’re at in modern-day society is a problematic relationship with sleep,” he said.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>“We know that sleep is fundamentally important at the most basic of biological levels,” he said. “But something strange has happened – sleep has received a stigma. There’s some kind of intonation which suggests that getting sufficient sleep is equivalent to being lazy. We wear this badge of sleep deprivation like some kind of honor emblem on our arm, and that’s profoundly misguided.”\u003c/p>\n\u003ch2>Additional Links\u003c/h2>\n\u003cul>\n\u003cli>\u003ca href=\"https://www.youtube.com/watch?v=yTIDkj9Tn58\">Watch the full episode of QUEST.\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201408261000\">Forum with Michael Krasny: sleep expert Matthew Walker\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://blogs.kqed.org/stateofhealth/2014/08/27/sleep-apps-myths-and-more-strategies-for-a-good-nights-rest/\">Sleep Apps, Myths and More: Strategies for a Good Night’s Rest\u003c/a>\u003c/li>\n\u003cli>\u003ca href=\"http://www.kqed.org/a/forum/R201311270930\">Forum with Dave Iverson: sleep therapy as a treatment for depression\u003c/a>\u003c/li>\n\u003c/ul>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/17514/catching-up-on-sleep-science","authors":["6444"],"categories":["quest_4","quest_12"],"tags":["quest_83","quest_135","quest_13038","quest_13048","quest_13044","quest_423","quest_13042","quest_13045","quest_13047","quest_13052","quest_13050","quest_13040","quest_13046","quest_12269","quest_13201","quest_13035","quest_1451","quest_11723","quest_10537","quest_1788","quest_13039","quest_13036","quest_1916","quest_13041","quest_9816","quest_13037","quest_2031","quest_13","quest_10538","quest_2655","quest_13034","quest_13051","quest_2893","quest_3021","quest_12094","quest_13043","quest_3071","quest_13049"],"featImg":"quest_72659","label":"source_quest_17514"},"quest_5553":{"type":"posts","id":"quest_5553","meta":{"index":"posts_1591205157","site":"quest","id":"5553","score":null,"sort":[1271174409000]},"guestAuthors":[],"slug":"producers-notes-in-search-of-a-better-nights-sleep","title":"Producer's Notes: In Search of a Better Night's Sleep","publishDate":1271174409,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>Nearly all of us have had the experience of waking up and feeling as though the restorative, rejuvenating effects of a good night's sleep had passed us by. I've had countless nights where sleep was either outright elusive or would come in fits and starts. As a result of producing this story I'm now more cognizant than ever that sleep is essential for our physical and mental well-being, that when we short-change this much-abused resource, there are repercussions broad and far-reaching, from weight gain to heart disease and depression. As the scientists in our \u003ca href=\"http://ww2.kqed.org/quest/video/catching-up-on-sleep-science\">QUEST sleep story\u003c/a> stated, how much each of us needs to sleep varies, based in part on our genetic makeup. Nonetheless, there are steps each of us can take to ensure that a good night's sleep is as close at hand as a pillow, hopefully night after night.\u003c/p>\n\u003cp>According to \u003ca href=\"http://med.stanford.edu/school/Psychiatry/narcolepsy/mignot.html\">Dr. Emmanuel Mignot of Stanford University\u003c/a>, \"many people are sleep deprived. In fact, there is a very simple way to know if you are sleep deprived, is if you feel awake all day long. If you don’t feel awake all day long, you probably don't get enough sleep, or if you have a sleep problem. Or if you use an alarm clock. That means that by definition, you’re not sleeping the extra half an hour that you need in the morning to really get your sleep debt completely abolished.\" Personally, I can't imagine waking up without an alarm clock during the work week. So I probably could benefit from another half-hour of sleep, at least. \u003c/p>\n\u003cp>If you're also having trouble with your sleep, another thing to keep in mind is sleep regularity. According to Dr. Mignot, it's important \"to go to bed roughly at the same time and to wake up at the same time. And getting the amount you need...the key is to assess how much sleep you really need to be fully rested, and then get that sleep in one period during the night at regular hours.\" Dr. Mignot also told me that some people who nap during the day will arrive at his clinic complaining of not being able to go to sleep at night. That's because napping abolishes some of the body's \"sleep homeostasis\" which basically states that the pressure to sleep increases the more we've been awake and that sleeping reduces this pressure. So by napping, you've eliminated some of this pressure which won't build up again until many hours later, initiating feelings of sleepiness.\u003c/p>\n\u003cp>Then, there is the issue of caffeine. I don't know too many people who can do without caffeine to stay alert during the day. Nonetheless, if we take caffeine in the afternoon, our sleep is likely to suffer. During my interview with Dr. Mignot, I was surprised to learn that alcohol can impair one's sleep as well, since alcohol is a depressant and should presumably make one sleepy. Dr. Mignot said, \"you have to avoid taking alcohol in the evening too late, because often it will produce sleep apnea, or a very dense sleep. And then you would wake up after a couple of hours unable to sleep, go back to sleep.\" Another factor that affects sleep for people in high, northern latitudes is the lack of daylight. As you may recall from the \u003ca href=\"http://ww2.kqed.org/quest/video/catching-up-on-sleep-science\">QUEST sleep story\u003c/a>, a circadian rhythm entrains our bodies to wake up and go to sleep, with daylight acting as the cue to set the master clock in the brain. So it's important to have plenty of external light so that your circadian clock isn't thrown off, as it may be if you're in Alaska or a similar region where daylight is a precious resource during the long winter months. Finally, I was surprised to discover that even the ambient temperature of one's bedroom can facilitate or hinder the ability to fall asleep. This is because at night the body's temperature dips slightly, initiating sleep onset. So if your bedroom is warmer than 70 degrees, and you're having trouble falling asleep, try setting the thermostat to 68 or maybe even a degree or two cooler. \u003c/p>\n\u003cp>The aforementioned are simple tips which may be of little help if you suffer from a sleep disorder like sleep apnea or restless leg syndrome. So it's important to seek the help of a physician who may recommend undergoing a sleep test to diagnose the source of your sleep difficulties. Here's wishing you sweet dreams.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\u003cp>\u003c/p>\n","blocks":[],"excerpt":"Nearly all of us have had the experience of waking up and feeling as though the restorative, rejuvenating effects of a good night's sleep had passed us by.","status":"publish","parent":0,"modified":1457732766,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":7,"wordCount":773},"headData":{"title":"Producer's Notes: In Search of a Better Night's Sleep | KQED","description":"Nearly all of us have had the experience of waking up and feeling as though the restorative, rejuvenating effects of a good night's sleep had passed us by.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Producer's Notes: In Search of a Better Night's Sleep","datePublished":"2010-04-13T16:00:09.000Z","dateModified":"2016-03-11T21:46:06.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"5553 http://www.kqed.org/quest/blog/2010/04/13/producers-notes-in-search-of-a-better-nights-sleep/","disqusUrl":"https://ww2.kqed.org/quest/2010/04/13/producers-notes-in-search-of-a-better-nights-sleep/","disqusTitle":"Producer's Notes: In Search of a Better Night's Sleep","videoEmbed":"https://www.youtube.com/watch?v=HW1HxGJAjqY","path":"/quest/5553/producers-notes-in-search-of-a-better-nights-sleep","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>Nearly all of us have had the experience of waking up and feeling as though the restorative, rejuvenating effects of a good night's sleep had passed us by. I've had countless nights where sleep was either outright elusive or would come in fits and starts. As a result of producing this story I'm now more cognizant than ever that sleep is essential for our physical and mental well-being, that when we short-change this much-abused resource, there are repercussions broad and far-reaching, from weight gain to heart disease and depression. As the scientists in our \u003ca href=\"http://ww2.kqed.org/quest/video/catching-up-on-sleep-science\">QUEST sleep story\u003c/a> stated, how much each of us needs to sleep varies, based in part on our genetic makeup. Nonetheless, there are steps each of us can take to ensure that a good night's sleep is as close at hand as a pillow, hopefully night after night.\u003c/p>\n\u003cp>According to \u003ca href=\"http://med.stanford.edu/school/Psychiatry/narcolepsy/mignot.html\">Dr. Emmanuel Mignot of Stanford University\u003c/a>, \"many people are sleep deprived. In fact, there is a very simple way to know if you are sleep deprived, is if you feel awake all day long. If you don’t feel awake all day long, you probably don't get enough sleep, or if you have a sleep problem. Or if you use an alarm clock. That means that by definition, you’re not sleeping the extra half an hour that you need in the morning to really get your sleep debt completely abolished.\" Personally, I can't imagine waking up without an alarm clock during the work week. So I probably could benefit from another half-hour of sleep, at least. \u003c/p>\n\u003cp>If you're also having trouble with your sleep, another thing to keep in mind is sleep regularity. According to Dr. Mignot, it's important \"to go to bed roughly at the same time and to wake up at the same time. And getting the amount you need...the key is to assess how much sleep you really need to be fully rested, and then get that sleep in one period during the night at regular hours.\" Dr. Mignot also told me that some people who nap during the day will arrive at his clinic complaining of not being able to go to sleep at night. That's because napping abolishes some of the body's \"sleep homeostasis\" which basically states that the pressure to sleep increases the more we've been awake and that sleeping reduces this pressure. So by napping, you've eliminated some of this pressure which won't build up again until many hours later, initiating feelings of sleepiness.\u003c/p>\n\u003cp>Then, there is the issue of caffeine. I don't know too many people who can do without caffeine to stay alert during the day. Nonetheless, if we take caffeine in the afternoon, our sleep is likely to suffer. During my interview with Dr. Mignot, I was surprised to learn that alcohol can impair one's sleep as well, since alcohol is a depressant and should presumably make one sleepy. Dr. Mignot said, \"you have to avoid taking alcohol in the evening too late, because often it will produce sleep apnea, or a very dense sleep. And then you would wake up after a couple of hours unable to sleep, go back to sleep.\" Another factor that affects sleep for people in high, northern latitudes is the lack of daylight. As you may recall from the \u003ca href=\"http://ww2.kqed.org/quest/video/catching-up-on-sleep-science\">QUEST sleep story\u003c/a>, a circadian rhythm entrains our bodies to wake up and go to sleep, with daylight acting as the cue to set the master clock in the brain. So it's important to have plenty of external light so that your circadian clock isn't thrown off, as it may be if you're in Alaska or a similar region where daylight is a precious resource during the long winter months. Finally, I was surprised to discover that even the ambient temperature of one's bedroom can facilitate or hinder the ability to fall asleep. This is because at night the body's temperature dips slightly, initiating sleep onset. So if your bedroom is warmer than 70 degrees, and you're having trouble falling asleep, try setting the thermostat to 68 or maybe even a degree or two cooler. \u003c/p>\n\u003cp>The aforementioned are simple tips which may be of little help if you suffer from a sleep disorder like sleep apnea or restless leg syndrome. So it's important to seek the help of a physician who may recommend undergoing a sleep test to diagnose the source of your sleep difficulties. Here's wishing you sweet dreams.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/5553/producers-notes-in-search-of-a-better-nights-sleep","authors":["6176"],"categories":["quest_4","quest_12","quest_3422","quest_3233"],"tags":["quest_423","quest_810","quest_1916","quest_2405","quest_2655","quest_2656","quest_2657","quest_2893"],"label":"quest"},"quest_2809":{"type":"posts","id":"quest_2809","meta":{"index":"posts_1591205157","site":"quest","id":"2809","score":null,"sort":[1245177867000]},"guestAuthors":[],"slug":"producers-notes-the-sweet-science-of-chocolate","title":"Producer's Notes: The Sweet Science of Chocolate","publishDate":1245177867,"format":"video","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>The scientific name for chocolate, Theobroma, translates to “food of the gods.” This delectable confection has been worshipped for centuries and the fervor for this sweet treat hasn’t abated yet. Scientists have been studying the putative health benefits of dark chocolate for over a decade, and their studies are showing that it shouldn’t necessarily be regarded as a guilty indulgence. \u003c/p>\n\u003cp>As seen in our QUEST story, \"\u003ca href=\"http://ww2.kqed.org/quest/video/the-sweet-science-of-chocolate\">The Sweet Science of Chocolate\u003c/a>,\" \u003ca href=\"http://nurseweb.ucsf.edu/www/ffengmb.htm\">UCSF’s Mary Engler\u003c/a> conducted a clinical trial that showed that a plant-based flavonoid, epicatechin, \u003ca href=\"//www.innovations-report.com/html/reports/studies/report-29769.html\">helped to promote healthy blood flow\u003c/a> in healthy patients. \u003c/p>\n\u003cp>Other researchers in the late ‘90’s, such as Adam Drenowski at the University of Washington, found that \u003ca href=\"http://www.cnn.com/HEALTH/indepth.food/sweets/chocolate.cravings/index.html\">chocolate helps trigger the release of endorphins\u003c/a>, while Daniele Piomelli of UC Irvine, conducted research on \u003ca href=\"http://www.chocolate.org/health/chocprescribe.html\">cannabinoids found in chocolate\u003c/a>. \u003c/p>\n\u003cp>And recent research suggested that \u003ca href=\"http://www.chocolate.org/health/memory.html\">chocolate could even be good for your memory\u003c/a>. There are other compounds present in chocolate which may have beneficial effects on your mind and body, such as serotonin, caffeine, theobromine, phenylethylamine, and polyphenols. Who knows what future chocolate research may yield, but in the meantime-- no joke here-- you might even be pumping \u003ca href=\"http://news.bbc.co.uk/2/hi/uk_news/england/coventry_warwickshire/8034540.stm\">chocolate-based fuels\u003c/a> into your gas tank!\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\u003cp>\u003c/p>\n","blocks":[],"excerpt":"Join QUEST TV Associate Producer Jenny Oh for a taste of the latest chocolate science.","status":"publish","parent":0,"modified":1457746758,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":6,"wordCount":210},"headData":{"title":"Producer's Notes: The Sweet Science of Chocolate | KQED","description":"Join QUEST TV Associate Producer Jenny Oh for a taste of the latest chocolate science.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Producer's Notes: The Sweet Science of Chocolate","datePublished":"2009-06-16T18:44:27.000Z","dateModified":"2016-03-12T01:39:18.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"2809 http://www.kqed.org/quest/blog/?p=2809","disqusUrl":"https://ww2.kqed.org/quest/2009/06/16/producers-notes-the-sweet-science-of-chocolate/","disqusTitle":"Producer's Notes: The Sweet Science of Chocolate","videoEmbed":"https://www.youtube.com/watch?v=WUwaidNGXaM","path":"/quest/2809/producers-notes-the-sweet-science-of-chocolate","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>The scientific name for chocolate, Theobroma, translates to “food of the gods.” This delectable confection has been worshipped for centuries and the fervor for this sweet treat hasn’t abated yet. Scientists have been studying the putative health benefits of dark chocolate for over a decade, and their studies are showing that it shouldn’t necessarily be regarded as a guilty indulgence. \u003c/p>\n\u003cp>As seen in our QUEST story, \"\u003ca href=\"http://ww2.kqed.org/quest/video/the-sweet-science-of-chocolate\">The Sweet Science of Chocolate\u003c/a>,\" \u003ca href=\"http://nurseweb.ucsf.edu/www/ffengmb.htm\">UCSF’s Mary Engler\u003c/a> conducted a clinical trial that showed that a plant-based flavonoid, epicatechin, \u003ca href=\"//www.innovations-report.com/html/reports/studies/report-29769.html\">helped to promote healthy blood flow\u003c/a> in healthy patients. \u003c/p>\n\u003cp>Other researchers in the late ‘90’s, such as Adam Drenowski at the University of Washington, found that \u003ca href=\"http://www.cnn.com/HEALTH/indepth.food/sweets/chocolate.cravings/index.html\">chocolate helps trigger the release of endorphins\u003c/a>, while Daniele Piomelli of UC Irvine, conducted research on \u003ca href=\"http://www.chocolate.org/health/chocprescribe.html\">cannabinoids found in chocolate\u003c/a>. \u003c/p>\n\u003cp>And recent research suggested that \u003ca href=\"http://www.chocolate.org/health/memory.html\">chocolate could even be good for your memory\u003c/a>. There are other compounds present in chocolate which may have beneficial effects on your mind and body, such as serotonin, caffeine, theobromine, phenylethylamine, and polyphenols. Who knows what future chocolate research may yield, but in the meantime-- no joke here-- you might even be pumping \u003ca href=\"http://news.bbc.co.uk/2/hi/uk_news/england/coventry_warwickshire/8034540.stm\">chocolate-based fuels\u003c/a> into your gas tank!\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/2809/producers-notes-the-sweet-science-of-chocolate","authors":["2100"],"categories":["quest_4","quest_12","quest_3422","quest_3233"],"tags":["quest_423","quest_478","quest_590","quest_641","quest_830","quest_983","quest_1010","quest_1108","quest_1122","quest_1124","quest_13201","quest_3351","quest_2141","quest_2178","quest_2259","quest_2588","quest_2853","quest_2893","quest_2921","quest_2922"],"label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. 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