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Barry Starr","firstName":"Dr. Barry","lastName":"Starr","slug":"dr-barry-starr","email":"bstarr@thetech.org","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Dr. Barry Starr (\u003ca href=\"https://twitter.com/geneticsboy\">@geneticsboy\u003c/a>) is a Geneticist-in-Residence at The Tech Museum of Innovation in San Jose, CA and runs their Stanford at The Tech program. The program is part of an ongoing collaboration between the \u003ca href=\"http://genetics.stanford.edu/\">Stanford Department of Genetics\u003c/a> and \u003ca href=\"http://www.thetech.org/\">The Tech Museum of Innovation\u003c/a>. Together these two partners created the \u003ca href=\"http://www.thetech.org/exhibits/permanent/index.php?sGalKey=gtwt&galKey=lt\">Genetics: Technology with a Twist\u003c/a> exhibition.\r\n\r\nYou can also see \u003ca href=\"https://ww2.kqed.org/science/author/dr-barry-starr/\">additional posts by Barry at KQED Science\u003c/a>, and read his \u003ca href=\"http://science.kqed.org/quest/author/dr-barry-starr/\">previous contributions\u003c/a> to \u003ca href=\"http://science.kqed.org/quest/\">QUEST\u003c/a>, a project dedicated to exploring the Science of Sustainability.","avatar":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g","twitter":"geneticsboy","facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"science","roles":["author"]},{"site":"quest","roles":["subscriber"]}],"headData":{"title":"Dr. Barry Starr | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/dr-barry-starr"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"home","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"quest_19237":{"type":"posts","id":"quest_19237","meta":{"index":"posts_1591205157","site":"quest","id":"19237","score":null,"sort":[1307373792000]},"guestAuthors":[],"slug":"dominant-isn%e2%80%99t-always-common","title":"Dominant isn't Always Common","publishDate":1307373792,"format":"aside","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/06/EyeColorMap21.jpg\">\u003cbr>\n\u003cem>Just because a trait is dominant does not mean it is common. Each color represents different levels of light eyes. Blue=80%+, teal=50-79%, olive=20-49%, brown=1-19%, black=none. Image courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:Light_eye_coloration_map.png\">Dark Tichondrias\u003c/a>\u003c/em>\u003c/p>\n\u003cp>One of the first things we’re taught in genetics is that some traits are dominant and others are recessive. And that the dominant traits trump the recessive ones.\u003c/p>\n\u003cp>So brown eyes trump blue eyes. And red hair is always trumped by other hair colors. And so on.\u003c/p>\n\u003cp>From this, people often jump to the conclusion that the dominant trait is also the most common one. This isn’t always the case and there is no reason it should be.\u003c/p>\n\u003cp>Whether or not a trait is common has to do with how many copies of that gene version (or allele) are in the population. It has little or nothing to do with whether the trait is dominant or recessive.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Let’s take eye color as an example. The decision on whether to have brown eyes or not is pretty much controlled by a single gene, \u003ca href=\"http://www.thetech.org/genetics/news.php?id=76\">OCA2\u003c/a>.\u003c/p>\n\u003caside class=\"alignright\">\u003ca href=\"https://www.kqed.org/futureofyou/tag/genetics\" target=\"_blank\" rel=\"noopener\">More on genetics\u003c/a>\u003c/aside>\n\u003cp>We can think of OCA2 as having two versions, brown and not-brown. The brown allele of OCA2 is dominant over the not-brown allele.\u003c/p>\n\u003cp>Nearly everyone in most of Africa has brown eyes. This isn’t because brown eyes are dominant over blue and green. Instead, it is because there are mostly brown alleles of OCA2 in the African population.\u003c/p>\n\u003cp>Northern Europe is a different story. In some parts of the continent, over 80% of the population has lighter colored eyes. Here the not-brown allele is more common even though it is recessive.\u003c/p>\n\u003cp>Now this allele isn’t exclusive, there are still brown-eyed folks in northern Europe. So why don’t their brown eyes dominate over time? Because in populations, dominant isn’t dominant over other people’s recessive gene versions. Your brown eyes can’t affect my kids’ eye color unless we get married.\u003c/p>\n\u003cp>Let’s do a thought experiment to make this clearer. To simplify things we’ll call brown eyes B and not-brown eyes b.\u003c/p>\n\u003cp>\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/06/AlleleGeneration.jpg\">\u003cbr>\n\u003cem>Without some sort of outside pressure, the ratio of blue to brown eyes stays the same.\u003c/em>\u003c/p>\n\u003cp>Remember, you will have brown eyes if you are BB or Bb and blue or green if you are bb. This is because brown (B) is dominant over blue and green (b).\u003c/p>\n\u003cp>Imagine we start out with eleven bb people and one Bb person. The Bb person has 4 kids with one of the bb folks and each bb couple also has 4 kids.\u003c/p>\n\u003cp>Using regular old Mendelian genetics, we'll have 20 bb people from our 5 bb couples and 2 Bb and 2 bb from our mixed couple. This is 2 people with brown eyes and 22 people with blue or green. The same ratio as we started with. Brown did not become more common.\u003c/p>\n\u003cp>Now these folks all pair up randomly and have 4 kids each. Since we aren't going to allow incest, the Bb folks will find a bb for a mate. If they have 4 kids each, then we have 44 bb and 4 Bb. Again the same eleven blue to one brown ratio. Whether an allele is dominant or not does not affect how common a trait is.\u003c/p>\n\u003cp>Now of course traits can \u003ca href=\"http://www.thetech.org/genetics/ask.php?id=411\">become more common\u003c/a> over time. The changes just don’t have anything to do with whether the trait is dominant or not.\u003c/p>\n\u003cp>If brown eyes gave an advantage, then it would start to become more common. Brown eyes would also become more common if a bunch of Africans moved in or many of the blue-eyed people were killed for some reason (witch burning?). And there are other ways too of getting more brown eyes in Europe. Or more blue eyes in Africa (see South Africa for example).\u003c/p>\n\u003cp>Dominant does not mean common. Which in some ways is a good thing considering diseases like Huntington’s disease that are dominant.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003ca href=\"http://www.thetech.org/genetics/ask.php?id=227\">Why some gene versions are dominant and some are recessive.\u003c/a>\u003c/p>\n\n","blocks":[],"excerpt":"A common genetic misconception is that dominant means common. Here Dr. Starr explains why dominant and recessive doesn't matter for how common a trait is.","status":"publish","parent":0,"modified":1542232003,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":22,"wordCount":701},"headData":{"title":"Dominant isn't Always Common | KQED","description":"A common genetic misconception is that dominant means common. Here Dr. Starr explains why dominant and recessive doesn't matter for how common a trait is.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Dominant isn't Always Common","datePublished":"2011-06-06T15:23:12.000Z","dateModified":"2018-11-14T21:46:43.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"19237 http://www.kqed.org/quest/blog/2011/06/06/dominant-isn%e2%80%99t-always-common/","disqusUrl":"https://ww2.kqed.org/quest/2011/06/06/dominant-isn%e2%80%99t-always-common/","disqusTitle":"Dominant isn't Always Common","path":"/quest/19237/dominant-isn%e2%80%99t-always-common","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/06/EyeColorMap21.jpg\">\u003cbr>\n\u003cem>Just because a trait is dominant does not mean it is common. Each color represents different levels of light eyes. Blue=80%+, teal=50-79%, olive=20-49%, brown=1-19%, black=none. Image courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:Light_eye_coloration_map.png\">Dark Tichondrias\u003c/a>\u003c/em>\u003c/p>\n\u003cp>One of the first things we’re taught in genetics is that some traits are dominant and others are recessive. And that the dominant traits trump the recessive ones.\u003c/p>\n\u003cp>So brown eyes trump blue eyes. And red hair is always trumped by other hair colors. And so on.\u003c/p>\n\u003cp>From this, people often jump to the conclusion that the dominant trait is also the most common one. This isn’t always the case and there is no reason it should be.\u003c/p>\n\u003cp>Whether or not a trait is common has to do with how many copies of that gene version (or allele) are in the population. It has little or nothing to do with whether the trait is dominant or recessive.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Let’s take eye color as an example. The decision on whether to have brown eyes or not is pretty much controlled by a single gene, \u003ca href=\"http://www.thetech.org/genetics/news.php?id=76\">OCA2\u003c/a>.\u003c/p>\n\u003caside class=\"alignright\">\u003ca href=\"https://www.kqed.org/futureofyou/tag/genetics\" target=\"_blank\" rel=\"noopener\">More on genetics\u003c/a>\u003c/aside>\n\u003cp>We can think of OCA2 as having two versions, brown and not-brown. The brown allele of OCA2 is dominant over the not-brown allele.\u003c/p>\n\u003cp>Nearly everyone in most of Africa has brown eyes. This isn’t because brown eyes are dominant over blue and green. Instead, it is because there are mostly brown alleles of OCA2 in the African population.\u003c/p>\n\u003cp>Northern Europe is a different story. In some parts of the continent, over 80% of the population has lighter colored eyes. Here the not-brown allele is more common even though it is recessive.\u003c/p>\n\u003cp>Now this allele isn’t exclusive, there are still brown-eyed folks in northern Europe. So why don’t their brown eyes dominate over time? Because in populations, dominant isn’t dominant over other people’s recessive gene versions. Your brown eyes can’t affect my kids’ eye color unless we get married.\u003c/p>\n\u003cp>Let’s do a thought experiment to make this clearer. To simplify things we’ll call brown eyes B and not-brown eyes b.\u003c/p>\n\u003cp>\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/06/AlleleGeneration.jpg\">\u003cbr>\n\u003cem>Without some sort of outside pressure, the ratio of blue to brown eyes stays the same.\u003c/em>\u003c/p>\n\u003cp>Remember, you will have brown eyes if you are BB or Bb and blue or green if you are bb. This is because brown (B) is dominant over blue and green (b).\u003c/p>\n\u003cp>Imagine we start out with eleven bb people and one Bb person. The Bb person has 4 kids with one of the bb folks and each bb couple also has 4 kids.\u003c/p>\n\u003cp>Using regular old Mendelian genetics, we'll have 20 bb people from our 5 bb couples and 2 Bb and 2 bb from our mixed couple. This is 2 people with brown eyes and 22 people with blue or green. The same ratio as we started with. Brown did not become more common.\u003c/p>\n\u003cp>Now these folks all pair up randomly and have 4 kids each. Since we aren't going to allow incest, the Bb folks will find a bb for a mate. If they have 4 kids each, then we have 44 bb and 4 Bb. Again the same eleven blue to one brown ratio. Whether an allele is dominant or not does not affect how common a trait is.\u003c/p>\n\u003cp>Now of course traits can \u003ca href=\"http://www.thetech.org/genetics/ask.php?id=411\">become more common\u003c/a> over time. The changes just don’t have anything to do with whether the trait is dominant or not.\u003c/p>\n\u003cp>If brown eyes gave an advantage, then it would start to become more common. Brown eyes would also become more common if a bunch of Africans moved in or many of the blue-eyed people were killed for some reason (witch burning?). And there are other ways too of getting more brown eyes in Europe. Or more blue eyes in Africa (see South Africa for example).\u003c/p>\n\u003cp>Dominant does not mean common. Which in some ways is a good thing considering diseases like Huntington’s disease that are dominant.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp>\u003ca href=\"http://www.thetech.org/genetics/ask.php?id=227\">Why some gene versions are dominant and some are recessive.\u003c/a>\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/19237/dominant-isn%e2%80%99t-always-common","authors":["6177"],"categories":["quest_4"],"tags":["quest_3451","quest_227","quest_3549","quest_1188","quest_3586","quest_1193","quest_3588","quest_3589","quest_3679","quest_3733"],"label":"quest"},"quest_11859":{"type":"posts","id":"quest_11859","meta":{"index":"posts_1591205157","site":"quest","id":"11859","score":null,"sort":[1296493206000]},"guestAuthors":[],"slug":"a-better-military-through-genetics","title":"A Better Military Through Genetics","publishDate":1296493206,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/01/Soldiers1.jpg\" alt=\"\">\u003c/a>\u003cem>Can genetics help them be all they can be?\u003c/em>\u003c/span>\u003c/p>\n\u003cp>A new \u003ca href=\"http://www.fas.org/irp/agency/dod/jason/hundred.pdf\">report\u003c/a> commissioned by the Department of Defense recommends that everyone in the military eventually get their DNA sequenced. The idea is that scientists can use this treasure trove of information to quickly learn a lot about which bits of DNA lead to which traits or diseases. The military brass would then use this information to better care for soldiers and to make a more effective fighting force.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>For example, maybe they will be able to find people who are more prone to suffer from post traumatic stress disorder. These folks could then be kept away from the front lines.\u003c/p>\n\u003cp>Or maybe they can find soldiers who are more likely to be resistant to certain diseases. These folks would be the ones sent to regions where those diseases are common. And so on.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Of course they will also find out many other things that may be more useful to society (and the soldier’s personal lives) like which bits of DNA predispose someone to diabetes, cancer, heart disease, etc. And which bits make someone more likely to be tall, strong, have dark hair or green eyes or anything else the scientists can measure.\u003c/p>\n\u003cp>This obviously has the potential for good but it still feels a bit creepy to me. Especially if the military misuses or abuses the information it gets.\u003c/p>\n\u003cp>Everyone (including the military) has to be careful not to over interpret the data. Just because a piece of DNA correlates with a lower risk of PTSD, that does not mean it is the only piece of DNA that does. It may just be one of many.\u003c/p>\n\u003cp>So you can imagine people who are at a higher risk for PTSD being moved to the front lines because an incomplete understanding of their DNA made them look like they were at a lower risk. These kinds of mistakes would be bad for the soldier and may eventually cost us a war.\u003c/p>\n\u003cp>There also needs to be some kind of oversight to prevent outright abuse by military officials who do not understand the limitations of our DNA knowledge. We need to make sure they don’t do what a \u003ca href=\"http://www.eeoc.gov/eeoc/newsroom/release/4-18-01.cfm\">railroad company did\u003c/a> a few years ago.\u003c/p>\n\u003cp>Back in 2001 railroad workers brought a suit against BNSF railroad. The suit alleges that the company secretly tested 125 workers for a DNA snippet that increases someone’s risk for developing carpal tunnel syndrome. The story was that BNSF wanted to be able to deny worker’s compensation for any of these workers that developed carpal tunnel syndrome because they had a pre-existing condition.\u003c/p>\n\u003cp>Besides being against the law, this was also just plain stupid on the part of the railroad. They did not understand that the DNA snippet was not really predictive and that it was one of many genetic factors that can lead to an increased risk. They basically tried to figure out what the elephant looked like from just its tail.\u003c/p>\n\u003cp>The military may also use genetics to exclude some people from jobs they’d like to do or from the military entirely. I am not sure we will ever know DNA well enough to justify this sort of thing but at the very least we need to be sure that the generals understand what we can and can’t learn from our DNA. And that we update the military head honchos constantly.\u003c/p>\n\u003cp>Once the cost of reading our DNA drops to $1000 or less, we’ll all eventually be getting our DNA sequenced. And if the military follows the report’s recommendations, then the military will be testing the waters of our genetic pool. We can all learn from the mistakes they make along the way. I just hope the learning process doesn’t endanger any of our soldiers. \u003c/p>\n\u003cp>\u003ca href=\"http://www.livescience.com/history/090429-military-experiment-1.html\">The 10 Most Outrageous Military Experiments\u003c/a>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7749295 -122.4194155\u003c/p>\n\n","blocks":[],"excerpt":"A new report recommends that all military people have their DNA sequenced to advance science and to create a better military. Can we trust the military to get this right - or anyone?","status":"publish","parent":0,"modified":1309991844,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":18,"wordCount":660},"headData":{"title":"A Better Military Through Genetics | KQED","description":"A new report recommends that all military people have their DNA sequenced to advance science and to create a better military. Can we trust the military to get this right - or anyone?","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"A Better Military Through Genetics","datePublished":"2011-01-31T17:00:06.000Z","dateModified":"2011-07-06T22:37:24.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"11859 http://www.kqed.org/quest/blog/2011/01/31/a-better-military-through-genetics/","disqusUrl":"https://ww2.kqed.org/quest/2011/01/31/a-better-military-through-genetics/","disqusTitle":"A Better Military Through Genetics","path":"/quest/11859/a-better-military-through-genetics","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2011/01/Soldiers1.jpg\" alt=\"\">\u003c/a>\u003cem>Can genetics help them be all they can be?\u003c/em>\u003c/span>\u003c/p>\n\u003cp>A new \u003ca href=\"http://www.fas.org/irp/agency/dod/jason/hundred.pdf\">report\u003c/a> commissioned by the Department of Defense recommends that everyone in the military eventually get their DNA sequenced. The idea is that scientists can use this treasure trove of information to quickly learn a lot about which bits of DNA lead to which traits or diseases. The military brass would then use this information to better care for soldiers and to make a more effective fighting force.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>For example, maybe they will be able to find people who are more prone to suffer from post traumatic stress disorder. These folks could then be kept away from the front lines.\u003c/p>\n\u003cp>Or maybe they can find soldiers who are more likely to be resistant to certain diseases. These folks would be the ones sent to regions where those diseases are common. And so on.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Of course they will also find out many other things that may be more useful to society (and the soldier’s personal lives) like which bits of DNA predispose someone to diabetes, cancer, heart disease, etc. And which bits make someone more likely to be tall, strong, have dark hair or green eyes or anything else the scientists can measure.\u003c/p>\n\u003cp>This obviously has the potential for good but it still feels a bit creepy to me. Especially if the military misuses or abuses the information it gets.\u003c/p>\n\u003cp>Everyone (including the military) has to be careful not to over interpret the data. Just because a piece of DNA correlates with a lower risk of PTSD, that does not mean it is the only piece of DNA that does. It may just be one of many.\u003c/p>\n\u003cp>So you can imagine people who are at a higher risk for PTSD being moved to the front lines because an incomplete understanding of their DNA made them look like they were at a lower risk. These kinds of mistakes would be bad for the soldier and may eventually cost us a war.\u003c/p>\n\u003cp>There also needs to be some kind of oversight to prevent outright abuse by military officials who do not understand the limitations of our DNA knowledge. We need to make sure they don’t do what a \u003ca href=\"http://www.eeoc.gov/eeoc/newsroom/release/4-18-01.cfm\">railroad company did\u003c/a> a few years ago.\u003c/p>\n\u003cp>Back in 2001 railroad workers brought a suit against BNSF railroad. The suit alleges that the company secretly tested 125 workers for a DNA snippet that increases someone’s risk for developing carpal tunnel syndrome. The story was that BNSF wanted to be able to deny worker’s compensation for any of these workers that developed carpal tunnel syndrome because they had a pre-existing condition.\u003c/p>\n\u003cp>Besides being against the law, this was also just plain stupid on the part of the railroad. They did not understand that the DNA snippet was not really predictive and that it was one of many genetic factors that can lead to an increased risk. They basically tried to figure out what the elephant looked like from just its tail.\u003c/p>\n\u003cp>The military may also use genetics to exclude some people from jobs they’d like to do or from the military entirely. I am not sure we will ever know DNA well enough to justify this sort of thing but at the very least we need to be sure that the generals understand what we can and can’t learn from our DNA. And that we update the military head honchos constantly.\u003c/p>\n\u003cp>Once the cost of reading our DNA drops to $1000 or less, we’ll all eventually be getting our DNA sequenced. And if the military follows the report’s recommendations, then the military will be testing the waters of our genetic pool. We can all learn from the mistakes they make along the way. I just hope the learning process doesn’t endanger any of our soldiers. \u003c/p>\n\u003cp>\u003ca href=\"http://www.livescience.com/history/090429-military-experiment-1.html\">The 10 Most Outrageous Military Experiments\u003c/a>\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7749295 -122.4194155\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/11859/a-better-military-through-genetics","authors":["6177"],"categories":["quest_4"],"tags":["quest_210","quest_227","quest_1192","quest_1194","quest_1200","quest_1213","quest_1824","quest_2162","quest_2266","quest_2328","quest_2724"],"featImg":"quest_19252","label":"quest"},"quest_9800":{"type":"posts","id":"quest_9800","meta":{"index":"posts_1591205157","site":"quest","id":"9800","score":null,"sort":[1288021832000]},"guestAuthors":[],"slug":"tracing-bad-and-dangerous-internet-science","title":"Tracing Bad (and Dangerous) Internet Science","publishDate":1288021832,"format":"standard","headTitle":"QUEST | KQED Science","labelTerm":{"site":"quest"},"content":"\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2010/10/RedBloodCells.jpg\" alt=\"\">\u003c/a>\u003cem>Despite what you read on the web, having Rh negative\u003cbr>blood does not protect you from HIV infection.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>A dangerous rumor has been spreading across the web that people with Rh negative blood are resistant or even immune to getting AIDS. They’re not. This is the “everyone is an expert” ethos of the web at its worst. \u003c/p>\n\u003cp>I was clued into this rumor through my \u003ca href=\"http://www.thetech.org/genetics/index.php\">Ask a Geneticist\u003c/a> website. A few months ago I started to get a few questions about whether or not having Rh negative blood protects people from getting infected by HIV, the virus that causes AIDS. I get occasional, random questions like these which I answer and then don’t give a second thought.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>But then I started to get more of these questions. And then I got one where someone asked me if being Rh negative was the same as having a \u003ca href=\"http://www.thetech.org/genetics/ask.php?id=111\">CCR5 delta-32 mutation\u003c/a>. That woke me up.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>Having two copies of the delta-32 version of the CCR5 gene does give some protection from HIV infection. But it has nothing to do with being Rh negative.\u003c/p>\n\u003cp>Being Rh negative has to do with red blood cells and CCR5 delta-32 with white blood cells. Not only that, but CCR5 and RhD are separate genes on separate chromosomes. (The RhD gene is the gene involved in being Rh negative.)\u003c/p>\n\u003cp>Clearly the questioner had put two and two together and came up with the answer that CCR5 delta-32 and being Rh negative were the same thing. Which is not the case. I decided to set out and try to find out where this rumor was coming from.\u003c/p>\n\u003cp>As I talk about \u003ca href=\"http://www.thetech.org/genetics/ask.php?id=381\">here in a previous post about Rh negative blood\u003c/a>, I traced it down to a couple of things. One was the supposed mystique associated with being Rh negative. The other had to do with a misunderstanding or misinterpretation of four separate bits of science.\u003c/p>\n\u003cp>This rumor probably isn’t that big a deal yet. It isn’t like the \u003ca href=\"http://www.pbs.org/newshour/updates/health/july-dec09/polio_08-24.html\">polio vaccine one\u003c/a> in Nigeria that has caused a resurgence of polio there. Or the one about \u003ca href=\"http://ww2.kqed.org/quest/2010/10/13/health-officials-to-consider-tightening-vaccine-exemptions/\">vaccines in general being risky\u003c/a> which is at least part of the reason for the whooping cough epidemic here in California.\u003c/p>\n\u003cp>But if the rumor that being Rh negative protects you from AIDS does take off, then people will get AIDS who otherwise might not have. Rh negative people who do risky things are as likely to get AIDS s anyone else. This is why I wanted to find out what was behind the rumor and try to nip it in the bud.\u003c/p>\n\u003cp>Hopefully the few people who read what I have written will trust me. I have no axe to grind here and really only care about the truth. Which, unfortunately, is not what a lot of people think about most scientists.\u003c/p>\n\u003cp>Scientists, along with many other experts, used to be seen as impartial. This is no longer true. In fact, the “everyone has to be an expert” idea probably springs from this general mistrust of authority.\u003c/p>\n\u003cp>If you don’t trust scientists, then you are going to try to interpret the science yourself. That is hard enough that you may come to the wrong conclusions.\u003c/p>\n\u003cp>So one answer might be to try to find or create a reliable source of science information. Some place where the scientists involved have no vested interest in the answer.\u003c/p>\n\u003cp>This used to be universities and the government but that ended long ago. We obviously need something else.\u003c/p>\n\u003cp>Maybe someone with way too much money like Google needs to set up a foundation where scientists can squash these rumors before they spread. The foundation would have to be independent and receive no outside funding and the scientists would have to work for no one else. This might be enough to give most of the public the confidence they need to trust the answers that come out of the foundation.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7749295 -122.4194155\u003c/p>\n\n","blocks":[],"excerpt":"A dangerous rumor has been spreading across the web that people with Rh negative blood are resistant or even immune to getting AIDS. They’re not. This is the “everyone is an expert” ethos of the web at its worst.","status":"publish","parent":0,"modified":1309992515,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":20,"wordCount":675},"headData":{"title":"Tracing Bad (and Dangerous) Internet Science | KQED","description":"A dangerous rumor has been spreading across the web that people with Rh negative blood are resistant or even immune to getting AIDS. They’re not. This is the “everyone is an expert” ethos of the web at its worst.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":"","schema":{"@context":"http://schema.org","@type":"Article","headline":"Tracing Bad (and Dangerous) Internet Science","datePublished":"2010-10-25T15:50:32.000Z","dateModified":"2011-07-06T22:48:35.000Z","image":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"}},"disqusIdentifier":"9800 http://science.kqed.org/quest/2010/10/25/tracing-bad-and-dangerous-internet-science/","disqusUrl":"https://ww2.kqed.org/quest/2010/10/25/tracing-bad-and-dangerous-internet-science/","disqusTitle":"Tracing Bad (and Dangerous) Internet Science","path":"/quest/9800/tracing-bad-and-dangerous-internet-science","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cspan class=\"left\">\u003ca href=\"http://www.kqed.org/quest\">\u003cimg src=\"http://ww2.kqed.org/quest/wp-content/uploads/sites/39/2010/10/RedBloodCells.jpg\" alt=\"\">\u003c/a>\u003cem>Despite what you read on the web, having Rh negative\u003cbr>blood does not protect you from HIV infection.\u003c/em>\u003c/span>\u003c/p>\n\u003cp>A dangerous rumor has been spreading across the web that people with Rh negative blood are resistant or even immune to getting AIDS. They’re not. This is the “everyone is an expert” ethos of the web at its worst. \u003c/p>\n\u003cp>I was clued into this rumor through my \u003ca href=\"http://www.thetech.org/genetics/index.php\">Ask a Geneticist\u003c/a> website. A few months ago I started to get a few questions about whether or not having Rh negative blood protects people from getting infected by HIV, the virus that causes AIDS. I get occasional, random questions like these which I answer and then don’t give a second thought.\u003c/p>\n\u003cp>\u003c!--more-->\u003c/p>\n\u003cp>But then I started to get more of these questions. And then I got one where someone asked me if being Rh negative was the same as having a \u003ca href=\"http://www.thetech.org/genetics/ask.php?id=111\">CCR5 delta-32 mutation\u003c/a>. That woke me up.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>Having two copies of the delta-32 version of the CCR5 gene does give some protection from HIV infection. But it has nothing to do with being Rh negative.\u003c/p>\n\u003cp>Being Rh negative has to do with red blood cells and CCR5 delta-32 with white blood cells. Not only that, but CCR5 and RhD are separate genes on separate chromosomes. (The RhD gene is the gene involved in being Rh negative.)\u003c/p>\n\u003cp>Clearly the questioner had put two and two together and came up with the answer that CCR5 delta-32 and being Rh negative were the same thing. Which is not the case. I decided to set out and try to find out where this rumor was coming from.\u003c/p>\n\u003cp>As I talk about \u003ca href=\"http://www.thetech.org/genetics/ask.php?id=381\">here in a previous post about Rh negative blood\u003c/a>, I traced it down to a couple of things. One was the supposed mystique associated with being Rh negative. The other had to do with a misunderstanding or misinterpretation of four separate bits of science.\u003c/p>\n\u003cp>This rumor probably isn’t that big a deal yet. It isn’t like the \u003ca href=\"http://www.pbs.org/newshour/updates/health/july-dec09/polio_08-24.html\">polio vaccine one\u003c/a> in Nigeria that has caused a resurgence of polio there. Or the one about \u003ca href=\"http://ww2.kqed.org/quest/2010/10/13/health-officials-to-consider-tightening-vaccine-exemptions/\">vaccines in general being risky\u003c/a> which is at least part of the reason for the whooping cough epidemic here in California.\u003c/p>\n\u003cp>But if the rumor that being Rh negative protects you from AIDS does take off, then people will get AIDS who otherwise might not have. Rh negative people who do risky things are as likely to get AIDS s anyone else. This is why I wanted to find out what was behind the rumor and try to nip it in the bud.\u003c/p>\n\u003cp>Hopefully the few people who read what I have written will trust me. I have no axe to grind here and really only care about the truth. Which, unfortunately, is not what a lot of people think about most scientists.\u003c/p>\n\u003cp>Scientists, along with many other experts, used to be seen as impartial. This is no longer true. In fact, the “everyone has to be an expert” idea probably springs from this general mistrust of authority.\u003c/p>\n\u003cp>If you don’t trust scientists, then you are going to try to interpret the science yourself. That is hard enough that you may come to the wrong conclusions.\u003c/p>\n\u003cp>So one answer might be to try to find or create a reliable source of science information. Some place where the scientists involved have no vested interest in the answer.\u003c/p>\n\u003cp>This used to be universities and the government but that ended long ago. We obviously need something else.\u003c/p>\n\u003cp>Maybe someone with way too much money like Google needs to set up a foundation where scientists can squash these rumors before they spread. The foundation would have to be independent and receive no outside funding and the scientists would have to work for no one else. This might be enough to give most of the public the confidence they need to trust the answers that come out of the foundation.\u003c/p>\n\u003cp>\u003c/p>\n\u003cp> 37.7749295 -122.4194155\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/quest/9800/tracing-bad-and-dangerous-internet-science","authors":["6177"],"categories":["quest_4"],"tags":["quest_120","quest_227","quest_348","quest_518","quest_848","quest_1197","quest_1375","quest_3032","quest_3152"],"featImg":"quest_19255","label":"quest"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. 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You ask the questions. You decide what Bay Curious investigates. 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You can also visit the MindShift website for episodes and supplemental blog posts or tweet us \u003ca href=\"https://twitter.com/MindShiftKQED\">@MindShiftKQED\u003c/a> or visit us at \u003ca href=\"/mindshift\">MindShift.KQED.org\u003c/a>","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Mindshift-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED MindShift: How We Will Learn","officialWebsiteLink":"/mindshift/","meta":{"site":"news","source":"kqed","order":"2"},"link":"/podcasts/mindshift","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/mindshift-podcast/id1078765985","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM1NzY0NjAwNDI5","npr":"https://www.npr.org/podcasts/464615685/mind-shift-podcast","stitcher":"https://www.stitcher.com/podcast/kqed/stories-teachers-share","spotify":"https://open.spotify.com/show/0MxSpNYZKNprFLCl7eEtyx"}},"morning-edition":{"id":"morning-edition","title":"Morning Edition","info":"\u003cem>Morning Edition\u003c/em> takes listeners around the country and the world with multi-faceted stories and commentaries every weekday. 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On Our Watch brings listeners into the rooms where officers are questioned and witnesses are interrogated to find out who this system is really protecting. 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